Training Program in Translational Research in Cancer

描述(由申请人提供)：翻译研究的成功完成需要结合最高质量的基础科学实验室研究和对发现的临床翻译的独特要求的基本理解。为了最有效地将基本研究成果转化为临床，应在研究发展的所有层面上考虑对这种举措的临床要求的认识，而不是将其视为基础实验室发展的复杂事后考虑。这项翻译研究的培训计划就是专注于这种整合。该翻译癌症研究博士后培训计划的主要目标是为候选人提供最高质量的培训和研究经验，使他们在发展学术界、政府和私营部门的研究事业方面具有竞争力。 该项目旨在培养博士后研究员(医学博士和博士研究生)。在开发和测试具有临床重要性的诊断和治疗策略方面。作为第一优先事项，研究员将在高度关键和成功的实验室接受培训，以确保最高水平的科学严谨性。此外，还设计了选修课和研讨会讨论系列，侧重于基本科学发现的临床翻译的独特要求。博士后研究员将参加两个临床相关的课程，并参加研讨会讨论系列。 从我们正在进行的科学项目中挑选教师的依据是：1.他们的研究质量最高；2.他们的翻译研究活动；以及3.他们在新泽西癌症研究所(CINJ)背景下对合作研究的承诺。为这个项目选择的所有导师都符合这三个标准。博士后候选人将是希望在临床相关研究中发展事业的博士研究生或医学博士(医学博士/博士)。完成他们的培训(在他们的临床研究员之后)，他们希望为学术医学的职业生涯做准备。博士后计划的毕业生将被期望竞争学术教员的职位，并应该竞争R01级别的入门级别的资金奖励。

DESCRIPTION (provided by applicant): The successful accomplishment of translational research requires a combination of the highest quality of basic science laboratory studies with a fundamental understanding of the unique requirements of clinical translation of the discoveries. In order to achieve the most efficient translation of basic findings to the clinic, the appreciation of the clinical requirements of such a move should be considered at all levels of research development rather than as a complicating afterthought to the basic laboratory development. This training program in translational research focuses on just this integration. The primary objective of this postdoctoral training program in translational cancer research is to provide candidates with the highest quality training and research experience so that they will be competitive in developing research careers in academia, government, and the private sector. This program has been designed to train postdoctoral fellows (both M.D. and Ph.D.) in the development and testing of clinically important diagnostic and therapeutic strategies. As the first priority, fellows will be trained in highly critical and successful laboratories to assure the highest level of scientific rigor. In addition, elective courses and seminar discussion series have been designed to focus on the unique requirements for clinical translation of the basic science findings. Postdoctoral fellows will be expected to take part in both the clinically relevant courses and participate in the seminar discussion series. Faculty has been chosen from our ongoing science programs based on: 1. The highest quality of their research; 2. Their translational research activities; and 3. Their commitment to collaborative research in the context of The Cancer Institute of New Jersey (CINJ). All of the preceptors chosen for this program meet these three criteria. Postdoctoral candidates will be either Ph.D. holders who wish to develop careers in clinically relevant research or M.D. (M.D./Ph.D.) finishing their training (following their clinical fellowships) who wish to prepare for careers in academic medicine. Graduates of the postdoctoral program will be expected to be competitive for academic faculty positions and should be competitive for entry level funding awards at the R01 level.