How do bone-active drugs increase patient survival?

骨活性药物如何提高患者的生存率？

• 批准号: nhmrc : GNT1079522
• 负责人: A/Pr Tri Phan
• 金额: $ 59.35万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/bone-active-drugs-patient-survival/1345290
• 关键词: How; do; bone; active; drugs

Bisphosphonates are a class of drugs used to prevent bone destruction in diseases such as osteoporosis. Evidence is emerging that these drugs also act on cells outside the skeleton to have additional beneficial effects, for example prolonging patient survival. This project will identify the cells affected and the mechanisms involved. With this knowledge, these drugs could be used more effectively and in different ways for the prevention or treatment of cancer and chronic human illnesses.

双膦酸盐是一类用于预防骨质疏松症等疾病中骨破坏的药物。有证据表明，这些药物也作用于骨骼外的细胞，具有额外的有益效果，例如延长患者的生存期。该项目将确定受影响的细胞和所涉及的机制。有了这些知识，这些药物可以更有效地以不同的方式用于预防或治疗癌症和慢性人类疾病。