CORE--HISTOPATHOLOGY
核心--组织病理学
基本信息
- 批准号:7142512
- 负责人:
- 金额:$ 7.61万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2005
- 资助国家:美国
- 起止时间:2005-09-10 至 2010-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The purpose of the Histopathology Facility (HF) is to facilitate research conducted by
investigators with peer-reviewed funding at FCCC by providing them with technical processing of cells and tissues as well as helping in the interpretation of results. The Facility's Technicians and Pathologist play a major support role in numerous research projects at the Center and their
contributions have been and continue to be of paramount importance in the establishment and
characterization of human cancer and other disease models. The Facility prepares, processes, and assists in evaluating tissues derived from experimental protocols developed by investigators with peer-reviewed funding. Most of the projects involve animal models of human cancer that require complex histological and/or cytological processing to determine morphological alterations, as well as to localize cancer-relevant gene products. The most frequently utilized services of the Facility include: laboratory animal autopsy, fixation, embedding and sectioning of paraffin-embedded tissues (7,000-8,000 per year), unstained paraffin sections for immunohistocnemistry (IHC) and LCM (10,000-14,000 per year), cryomicrotomy (100-200 per year), special stains (500-700 per year), immunohistochemistry (2,500-3,500 per year), in situ hybridization (100-200 per year), autoradiography (100-200 per year), digital microphotography (1,000-2,500 per year), and interpretative histopathology (7,000-10,000 HE and IHC slides signed-out per year). During the last CCSG funding cycle we have seen a significant increase in all services rendered as exemplified by the doubling in number of embedded and sectioned tissues (110% increase) and in the immunohistochemical work (120% increase). Furthermore, during 2000-2004 we implemented new technology such as tissue microarray sectioning and a Web-based Experimental Histopathology database. The Histopathology Facility also provides support to the Laboratory Animal Health Facility in quality control and animal health monitoring activities, as well as processing support to the Tumor Bank and the Research Cytogenetics and Laser Capture Microdissection Facilities. The HF is used by 33 investigators with peer-reviewed funding in 10 different Programs from all three Divisions. Eighty-nine percent (86%) of its use is for studies supported with peer-reviewed funding.
组织病理学设施(HF)的目的是促进进行的研究
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Robert C Young其他文献
Anticholinergic effects and plasma desipramine levels
抗胆碱能作用和血浆地昔帕明水平
- DOI:
- 发表时间:
1980 - 期刊:
- 影响因子:0
- 作者:
M. Rudorfer;Robert C Young - 通讯作者:
Robert C Young
Age and Serum Fluphenazine Concentrations
年龄与氟奋乃静血清浓度
- DOI:
10.1038/sj.npp.1380230 - 发表时间:
2003-07-25 - 期刊:
- 影响因子:7.100
- 作者:
James J Weisbard;Robert C Young - 通讯作者:
Robert C Young
Robert C Young的其他文献
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{{ truncateString('Robert C Young', 18)}}的其他基金
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