Urothelial Cell Physiology in Normal and Disease States

正常和疾病状态下的尿路上皮细胞生理学

• 批准号: 7001822
• 负责人: RICARDO SABAN
• 金额: $ 0.6万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-15 至 2006-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7001822
• 关键词: meeting /conference /symposium; physiology; travel; urinary bladder epithelium; urinary tract disorder

DESCRIPTION (provided by applicant): The present application is in support of 2-days symposium entitled "Urothelial Cell Physiology in Normal and Disease States" (http://www.urothelium2005.com) that was accepted by the International Physiology as satellite and will precede (March 29-30, 2005) the primary event (XXXV International Congress of Physiological Sciences). This symposium will be held in San Diego, CA. The symposium specific objectives are: 1 .To review bladder physiology. 2. To raise awareness of clinical aspects of lower urinary tract dysfunction including: detrusor instability, stress incontinence, interstitial cystitis, bladder cancer, infection, inflammation, and immunity. 3. To identify new post-genomic research approaches. The symposium specific goals are: 1. To attract new scientists to this important area or research. 2.To stimulate the participation of postdoctoral fellows and graduate students by providing travel awards for selected poster presentations. In order to accomplish these goals, 35 (21 national and 14 international) world's experts in UT physiology, pathology, and clinics will introduce the clinical aspects of the disease followed by the latest accomplishments in basic research. The symposium agenda is divided in 7 podium sections and one poster presentation. The podium sections include: I) Bladder Physiology; II) Genomics of bladder detrusor function; III) Urothelial Permeability; IV) Growth Factors; V) Sensory Peptides; VI) Angiogenesis and Lymphangiogenesis; and VII) Bladder Pathology (cancer and infection). In each of the sections key note speakers and outstanding researchers will address the most relevant aspects of the translational research. In this context, Prof. William C. de Groat (University of Pittsburgh) will review the basic aspects of bladder physiology and Dr. Karl-Erik Andersson (Lund University) will introduce the clinical an overview about the functional and disease implications of uroplakins whereas Prof. Scott-Hultgren (Washington U) will discuss the molecular basis of persistent bladder infections. The bladder cancer discussion will be chaired by Drs. Robert Hurst (Oklahoma U) and Jenny Southgate (U. York).

描述（由申请人提供）： 本申请支持为期2天的题为“正常和疾病状态下的尿路上皮细胞生理学”的专题讨论会（http：www.urothelium2005.com），该专题讨论会被国际生理学协会接受为附属会议，并将在主要活动（第三十五届国际生理科学大会）之前（2005年3月29-30日）举行。本次研讨会将在加利福尼亚州圣地亚哥举行。本次研讨会的具体目标是：1。回顾膀胱生理学。2.提高对下尿路功能障碍临床方面的认识，包括：逼尿肌不稳定、压力性尿失禁、间质性膀胱炎、膀胱癌、感染、炎症和免疫。3.确定新的后基因组研究方法。 本次研讨会的具体目标是：1.以吸引新的科学家到这个重要的领域或研究。2.通过为选定的海报展示提供旅行奖励，鼓励博士后研究员和研究生的参与。为了实现这些目标，35名（21名国家和14名国际）世界UT生理学，病理学和临床专家将介绍该疾病的临床方面，然后是基础研究的最新成就。研讨会议程分为7个讲台部分和一个海报展示。讲台部分包括：I）膀胱生理学; II）膀胱逼尿肌功能的基因组学; III）尿路上皮渗透性; IV）生长因子; V）感觉肽; VI）血管生成和淋巴管生成;和VII）膀胱病理学（癌症和感染）。在每一部分中，主讲人和杰出的研究人员将讨论翻译研究的最相关方面。在这种背景下，威廉C。de Groat（匹兹堡大学）将回顾膀胱生理学的基本方面，Karl-Erik Andersson博士（隆德大学）将介绍尿斑蛋白的临床功能和疾病意义，而Scott-Hultgren教授（华盛顿大学）将讨论持续性膀胱感染的分子基础。膀胱癌讨论将由罗伯特赫斯特博士（俄克拉荷马州U）和珍妮索斯盖特（U）主持。约克）。