CSHL Conference on Germ Cells

描述（由申请人提供）：生殖系是专门用于产生配子的组织；它包括卵母细胞和精子，以及未成熟的生殖细胞，如生殖系干细胞。性腺的体细胞组织与生殖系的正常发育和健康密切相关。种系组织具有巨大的实用和学术意义。它很可能是患病或受伤个体组织替代干细胞的最终来源，它影响避孕和生育问题。因此，种系生物学对医学和农业都至关重要。重大的智力和技术进步促使生殖细胞研究取得了令人兴奋的新发现。这一令人印象深刻的进展源于对脊椎动物和无脊椎动物的一系列研究。因此，来自不同技术和学术领域的研究人员聚集在一起分享他们的见解和发现是至关重要的。生殖细胞会议将于2006年10月11日至15日在冷泉港实验室举行。本次会议将提供一个公共论坛，讨论生殖细胞研究的各个方面，从早期胚胎的原始生殖细胞规范到成人配子的功能。会议将包括对多种生物的生殖细胞的研究，包括模式生物和人类。我们预计将吸引250-300名来自世界各地的参与者。在这个重要的研究领域，没有类似规模的竞争会议。平台演讲选择了八个广泛的主题：生殖细胞特性，生殖细胞模式和规格，配子发生和受精，生殖系程序，表观遗传调控，RNA调控，生殖系干细胞，以及全能性和重编程。每届会议将由该领域的两位专家组织和共同主持。发言者一般包括主席和每届会议额外邀请的一到两名发言者；其余的将从提交的摘要中选择。我们将鼓励青年科学家在平台上发表演讲。我们还将确保科学家之间的互动时间，特别是在用餐和海报会议期间。

DESCRIPTION (provided by applicant): The germ-line is the tissue specialized for generation of gametes; it includes oocytes and sperm in addition to immature germ cells such as germ-line stem cells. The somatic tissues of the gonad are intimately linked with the correct development and health of the germ-line. The germ-line tissue is of tremendous practical and scholarly significance. It may well be the ultimate source of stem cells for tissue replacement in diseased or injured individuals, and it impacts issues of both contraception and fertility. Therefore, germ-line biology is crucial for both medicine and agriculture. Major intellectual and technical advances have spurred new and exciting findings in germ cell research. This impressive progress derives from a range of studies in both vertebrates and invertebrates. It is, therefore, critical that researchers from diverse technical and academic arenas be brought together to share their insights and discoveries. The Germ Cells meeting will be held October 11-15, 2006 at the Cold Spring Harbor Laboratory. This meeting will provide a public forum for discussion of all aspects of germ cell research, from specification of primordial germ cells in the early embryo to the function of gametes in adults. The meeting will embrace investigations of germ cells in diverse organisms, including model organisms and humans. We expect to attract 250-300 participants from around the world. There are no competing meetings of similar scope in this important research area. Eight broad topics have been chosen for platform presentations: Germ Cell Traits, Germ Cell Patterning and Specification, Gametogenesis and Fertilization, Germ-line Programs, Epigenetic Regulation, RNA Regulation, Germ-line Stem Cells, and Totipotency and Reprogramming. Each session will be organized and co-chaired by two experts in the field. Speakers generally will include the chairs plus one or two additional invited speakers for each session; the remainder will be selected from submitted abstracts. We will encourage platform presentations from young scientists. We will also ensure time for interactions between scientists, particularly during meals and in poster sessions.