HU/JHU Head and Neck Cancer Translational Research and *

HU/JHU 头颈癌转化研究和*

• 批准号: 7129011
• 负责人: XINBIN GU
• 金额: $ 19.52万
• 依托单位: HOWARD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2009-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7129011
• 关键词: HU; JHU; Head; Neck; Cancer

DESCRIPTION (provided by applicant): Head and neck cancer is the sixth most common cancer worldwide, the seventh most common solid tumor in the United States. The incidence of head and neck cancer in African American men has been approximately two times higher than that of non African American men with a lower 5-year relative survival (36.2% vs. 47.6%). Howard University Medical Institutions is a minority-serving educational institution and medical center that is an important educational and clinical resource in the Washington DC/ Baltimore metropolitan area and serves a large community of low-income African American patients. However, recruitment and support for translational research efforts at Howard University has significant challenges. The goal of this proposal is to create a collaborative environment to enhance translational research and education related to head and neck cancer at the Howard University Medical Institutions through a highly collaborative effort between the Howard University Medical Institutions and the Head and Neck Cancer Center at the Johns Hopkins Medical Institutions. This collaboration is focused on translational research and research training as well as educational efforts focused on enhancing head and neck cancer translational research and impact on the Howard Medical Institutions community. Specific aims will be: 1) to support collaborative cancer research projects between the Howard University Medical Institutions and the Head and Neck Cancer Center and Sidney Kimmel Cancer Center at Johns Hopkins 2) to provide collaborative training and mentoring program for promoting Howard medical and dental students and faculty in cancer research, 3) to establish education programs that advance the knowledge of translational cancer research as it applies to etiology, prevention, diagnosis, and treatment of head and neck cancer in the context of minority-serving institutions. These aims will be promoted and coordinated in a synergistic manner, such that they reinforce the creation of a culture of collaborative translational research within the Howard University Cancer Center as well as an effective long-term partnership with investigators at the Johns Hopkins Medical Institutions. These goals will be pursued by directed mentorship of individuals at Howard Medical Institutions to develop as independent investigators via traditional mechanisms of the National Cancer Institute.

描述（由申请人提供）： 头颈癌是全球第六大常见癌症，在美国第七大常见实体瘤。非裔美国男性的头颈癌发病率大约是非裔美国男性的两倍，且 5 年相对生存率较低（36.2% vs. 47.6%）。霍华德大学医疗机构是一所为少数族裔服务的教育机构和医疗中心，是华盛顿特区/巴尔的摩大都市区的重要教育和临床资源，为大量低收入非裔美国患者提供服务。然而，霍华德大学转化研究工作的招募和支持面临着巨大的挑战。该提案的目标是通过霍华德大学医疗机构和约翰·霍普金斯医疗机构头颈癌中心之间的高度合作，创建一个协作环境，以加强霍华德大学医疗机构与头颈癌相关的转化研究和教育。此次合作的重点是转化研究和研究培训以及教育工作，重点是加强头颈癌转化研究和对霍华德医疗机构社区的影响。具体目标是：1）支持霍华德大学医疗机构与约翰霍普金斯大学头颈癌症中心和悉尼金梅尔癌症中心之间的合作癌症研究项目2）提供协作培训和指导计划以促进霍华德医学和牙科学生和教师进行癌症研究，3）建立教育计划以提高转化癌症研究的知识，因为它适用于头颈癌的病因学、预防、诊断和治疗 为少数族裔服务的机构。这些目标将以协同方式促进和协调，从而加强霍华德大学癌症中心内部合作转化研究文化的创建，以及与约翰·霍普金斯医疗机构研究人员的有效长期合作伙伴关系。这些目标将通过对霍华德医疗机构的个人进行直接指导来实现，以通过国家癌症研究所的传统机制发展为独立研究者。