Predoctoral Training in Molecular Biopysics

描述(由申请人提供)：这项新提案寻求美国国立卫生研究院对 加州大学分子生物物理学研究生培养计划 科罗拉多州，博尔德。我们迅速扩大博士前培训的目标是 该计划是为杰出的、高度积极的生物物理学学生做好准备 在学术界或工业界从事富有成效的研究工作。27名培训教员 是一支杰出的、国际公认的调查小组，他们来自 三个系：化学和生物化学；分子、细胞和 发育生物学和化学工程。他们的研究包括 许多合作项目，范围从高分辨率的结构研究 蛋白质和核酸，到物理、计算和化学分析 酶和信号蛋白机制，结构和动力学分析 从大型超分子复合体到细胞生理学的生物物理研究， 到制药开发和组织工程。该项目始于1997年 作为一次非正式的超级小组会议，随后正式确立为 分子生物物理学系间研究生证书课程 1999-2000年。完成本课程的学生将获得来自 研究生院承认他们在分子生物物理学方面的研究生培训， 除了他们的国内部门授予的博士学位。每个学生开始 在他们的家庭部门、三个实验室开设核心课程的第一年 轮换和教学职责。在第一年结束时，一位论文导师 入选，论文研究开始。在第二年及以后， 学生选修与他们的研究项目相关的认可课程。必需的 课程作业包括一门研究伦理学课程和两门附加课程。 从已批准的列表中选择。所选课程之一必须是 《分子生物物理学技术》或《分子生物物理学进展》， 两者都是专门为培训计划开发的。在第二节的末尾 年，笔试和口试分析准备情况 学生进入博士候选人资格，并评估提出的论文项目。 在接下来的每一年，研究报告和与教职员工的会议 委员会就攻读博士学位的进展提供反馈。所有受训人员 和培训教员预计将参加联合国儿童基金会 生物物理学超级小组和研讨会系列。那些正在考虑 生物技术职业生涯可以选择在以下位置完成可选的实验室实习 当地几家生物技术公司之一。典型的学生将获得一个 在入学后5-6年内从所在部门获得博士学位，然后继续 博士后培训和在学术界的职业生涯或 制药/生物技术公司。

DESCRIPTION (provided by applicant): This new proposal seeks NIH support for the Molecular Biophysics Graduate Training Program at the University of Colorado, Boulder. The goal of our rapidly expanding predoctoral training program is to prepare exceptional, highly motivated biophysics students for productive research careers in academia or industry. The 27 training faculty are an outstanding, internationally recognized group of investigators from three departments: Chemistry & Biochemistry; Molecular, Cellular & Developmental Biology; and Chemical Engineering. Their research, which includes many collaborative projects, ranges from high resolution structural studies of proteins and nucleic acids, to physical, computational, and chemical analysis of enzyme and signaling protein mechanisms, to structural and kinetic analysis of large supermolecular complexes, to biophysical studies of cell physiology, to pharmaceutical development and tissue engineering. The program began in 1997 as an informal supergroup meeting, then was formally established as the Molecular Biophysics Interdepartmental Graduate Certificate Program in AY1999-2000. Students who complete this program receive a certificate from the Graduate School acknowledging their graduate training in Molecular Biophysics, in addition to the Ph.D. awarded by their home department. Each student begins the first year with Core courses in their home department, three laboratory rotations, and teaching duties. At the end of the first year, a thesis advisor is selected and thesis research commences. During the second year and beyond, the student takes approved courses relevant to their research project. Required coursework includes a research ethics course and two additional courses selected from an approved list. One of the selected courses must be either "Techniques in Molecular Biophysics" or "Advances in Molecular Biophysics", both developed specifically for the training program. At the end of the second year, written and oral qualifying examinations analyze the readiness of the student to advance to Ph.D. candidacy and evaluate the proposed thesis project. In each subsequent year, a research presentation and meeting with a faculty committee provides feedback on progress toward the Ph.D. degree. All trainees and training faculty are expected to participate in regular meetings of the Biophysics Supergroup and Seminar Series. Those students considering a biotechnology career can elect to complete an optional laboratory internship at one of several local biotechnology companies. The typical student will obtain a Ph.D. from their home department within 5-6 years of matriculation, then go on to postdoctoral training and a career in academia or with a pharmaceutical/biotechnology company.