CORE-- Biomarkers

核心——生物标志物

• 批准号: 6875464
• 负责人: JAMES A SWENBERG
• 金额: $ 31.04万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-04-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6875464
• 关键词: DNA damage; biomarker; biomedical facility; environmental health; genotype; immunocytochemistry; mass spectrometry; microarray technology; proteomics

Description (provided by applicant): The goal of the Biomarker Facility Core is to provide access to state of the art facilities for mass spectrometry, microarray, proteomics, metabolomics, mouse genotyping, DNA damage and immunohistochemistry for members of the CEHS to facilitate and enhance research on environmentally related disease. This will be accomplished by the following objectives: 1) to make available to Center members well equipped laboratories for analytical, molecular, genomic and histochemical biomarkers; 2) to assist Center members with experimental design, tissue collection and assays of various biomarkers; 3) to foster the application of biomarkers in pilot projects and new collaborative research projects; 4) to provide education and training in methods related to biomarkers.

描述（由申请人提供）：生物标志物设施核心的目标是提供访问质谱，微阵列，蛋白质组学，代谢组学，鼠标的最先进设施 CEHS成员的基因分型，DNA损伤和免疫组织化学促进和 增强有关环境相关疾病的研究。这将通过以下目标来实现：1）为中心成员提供良好的实验室，用于分析，分子，基因组和组织化学生物标志物； 2）协助中心成员进行实验设计，组织收集和各种生物标志物的测定； 3）促进生物标志物在试点项目和新的合作研究项目中的应用； 4）提供与生物标志物相关的方法的教育和培训。