Strengthening Botanical CAM Research: A Collaboration between CUNY and Columbia

描述(由申请者提供)：这是纽约城市大学(CUNY)和哥伦比亚大学内科和外科医学院合作的CAM研究开发能力增强项目。这两个机构的一个强项是植物学研究，这将是该项目的重点。纽约州立大学雷曼学院将作为主要的少数族裔服务机构(MSI)，但其他CUNY MSI也将参与该项目。雷曼兄弟拥有CUNY的植物科学博士项目，并拥有一批在基础植物生物学研究方面具有特殊实力的教职员工。此外，纽约植物园的研究人员将参与这项研究开发计划。纽约植物园距离雷曼兄弟不到一英里，也是CUNY博士项目的合作伙伴。哥伦比亚大学的罗森塔尔中心在药用植物的临床和基础科学研究方面创造了既定的记录。拟议的计划由著名合作者Edward Kennelly博士(雷曼)和Fredi Kronenberg博士(哥伦比亚)领导，有两个具体目标：在CUNY和哥伦比亚大学的研究人员之间开发以植物学为导向的CAM合作研究项目，提交给NIH作为R01或R21申请；以及在NIH研究拨款申请过程中教育CUNY调查人员。该项目将向纽约州立大学的十名植物学研究人员开放。这些目标将通过研究开发和优先事项设定两个阶段的计划来实现。研究开发阶段将使纽约大学和哥伦比亚大学的研究人员有机会通过每月一系列的研讨会了解彼此的工作。纽约州立大学的研究人员将参加两个继续医学教育课程：现代临床实践中的植物医学和营养学：营养与健康：科学和临床应用的现状，让他们对美国植物药物的使用有一个广泛的了解。还描述了CUNY教职员工参加关于基金撰写、机构审查委员会和CAM特定问题的研讨会的其他机会。在优先设置阶段，完成第一个研究开发阶段的纽约州立大学教职员工将被要求为NIH的研究申请制定一份概念文件。这些概念文件将由哥伦比亚大学的适当研究人员进行审查，并将选出最多三份概念文件进行密集开发。基于CUNY的研究优势，我们预计可能会在民族植物学、癌症化学预防、传统亚洲医学和代谢工程领域开发与CAM相关的研究项目。我们预计在项目期结束后的一年内，将向NIH提交几个与植物学相关的R21或R01的CAM申请。

DESCRIPTION (provided by applicant): This is a collaborative CAM research development capability enhancement program between City University of New York (CUNY) and Columbia University College of Physicians and Surgeons. An area of strength for both institutions is in botanical studies, and this will be the focus of the project. Lehman College, CUNY will serve as the lead minority-serving institution (MSI), but other CUNY MSIs will also participate in the project. Lehman houses CUNY's Plant Science doctoral program, and has a number of faculty with particular strength in basic plant biology research. In addition, researchers at the New York Botanical Garden, located less than a mile from Lehman and a partner in CUNY's doctoral program, will participate in this research development program. Columbia University's Rosenthal Center brings an established record in clinical and basic science research in medicinal plants. The proposed program, headed by established collaborators Dr. Edward Kennelly (Lehman) and Dr. Fredi Kronenberg (Columbia), has two specific aims: developing collaborative botanically-oriented CAM research projects between CUNY and Columbia researchers for submission to NIH as R01 or R21 applications; and educating CUNY investigators on the NIH research grant application process. The program will be open to ten CUNY botanical researchers. The aims will be accomplished through a two-stage program of research development and priority setting. The research development stage will give CUNY and Columbia researchers a chance to learn about each others' work though a monthly seminar series. The CUNY researchers will attend two continuing medical education courses "Botanical Medicine in Modern Clinical Practice" and on nutrition "Nutrition and Health: State of the Science and Clinical Applications" to give them a broad view of how botanicals are used in the US. Additional opportunities for CUNY faculty to participate in workshops on grant writing, institutional review boards, and CAM-specific issues for scientific paper writing are described. In the priority-setting stage, CUNY faculty who have completed the first research development stage will be asked to develop a concept paper for an NIH research application. The concept papers will be reviewed by appropriate Columbia researchers, and up to three concept papers will be selected for intense development. Based on the research strengths at CUNY we anticipate that CAM-related research projects may be developed in the areas of ethnobotany, cancer chemoprevention, traditional Asian medicine, and metabolic engineering. We anticipate that within a year after the end of the project period, several R21 or R01 botanically-related CAM applications will be submitted to NIH.