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CYP Genes and the Generation of Oxidative Stress

CYP Genes and the Generation of Oxidative Stress
CYP 基因与氧化应激的产生
批准号：
7326007
负责人：
JOHN J STEGEMAN
金额：
$63.38万
依托单位：
WOODS HOLE OCEANOGRAPHIC INSTITUTION
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-05-10 至 2012-02-29
来源：
https://reporter.nih.gov/project-details/7326007
关键词：
2-tert-butylhydroquinoneAddressAgonistAromatic HydrocarbonsAromatic Polycyclic HydrocarbonsAryl Hydrocarbon ReceptorBenzo(a)pyreneBindingCYP1A1 geneCell LineCellsChemicalsConfocal MicroscopyCytochrome P450DNA DamageDefectDevelopmentDoseEmbryoEndothelial CellsEnzymesFamily memberFishesGene ExpressionGene Expression ProfilingGene FamilyGenerationsGenesGlobal ChangeHepatocyteMammalsMeasuresMitochondriaModelingNucleic Acid Regulatory SequencesOligonucleotidesOxidantsOxidation-ReductionOxidative StressPathologyPathway interactionsPatternPolymerase Chain ReactionPredispositionProcessProductionProteinsPurposeReaction TimeReactive Oxygen SpeciesRegulationRelative (related person)ReporterResearch PersonnelResponse ElementsRetrotransposonReverse Transcriptase Polymerase Chain ReactionRoleSamplingSourceSystemTechnologyTestingTetrachlorodibenzodioxinToxic effectTranscriptTranslationsXenobioticsZebrafishbiological adaptation to stresscarbonyl reductase (NADPH)in vivoknock-downmorpholinenoveloxidative DNA damageprogramsresearch studytoxicant

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