WHCOHH: Harmful algal bloom dynamics and epigenetic mechanism of toxin action

WHCOHH：有害藻华动态和毒素作用的表观遗传机制

• 批准号: 8550044
• 负责人: JOHN J STEGEMAN
• 金额: $ 38.48万
• 依托单位: WOODS HOLE OCEANOGRAPHIC INSTITUTION
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-24 至 2017-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8550044
• 关键词: Address; Adult; Advisory Committees; Affect; Archives; Area; Biological Models; Communication; Community Health Education; Community Outreach; Data; Development; Dinophyceae; Ensure; Epigenetic Process; Evaluation; Exposure to; Fostering; Goals; Grant; Information Dissemination; Life; Link; Maine; Marine Toxins; Mission; Modeling; Monitor; National Institute of Environmental Health Sciences; Neurotoxins; Organism; Performance; Physiological; Policies; Population Dynamics; Process; Production; Public Health; Reporting; Research; Research Personnel; Resources; Risk; Sampling; Societies; Structure; System; Technology; Toxin; harmful algal blooms; improved; insight; meetings; member; novel; predictive modeling; programs; public health relevance; toxicant; web page

DESCRIPTION (provided by applicant) This Program Project application will employ novel remote sampling technologies to achieve new insights into the population dynamics of known and emerging HAB threats, and to address critical mechanisms of toxin action, linking developmental exposures to adult consequences. The Center will be overseen and guided by the Director and Deputy Director. The aims of the Administrative Core are to: 1) Facilitate communication, planning, integration and interaction among Center members, so that the goals and scientific objectives of the Center are achieved. 2) Provide and maintain an administrative structure to oversee and monitor the financial aspects of the Center, including grants management. 3) Establish a structure that will support effective communication and planning with contribution from all Center investigators, through an Internal Advisory Committee. 4) Establish an External Advisory Committee, which will review the Center programs and advise the Director and Deputy Director. 5) Implement evaluation mechanisms, utilizing both Internal and External Advisory Committees. 6) Establish and maintain public and private web pages for the dissemination of information and for data transfer and communication 7) Pursue interactions between the WHCOHH and other OHH Centers, as well as with other EHS Centers, in order to expand the reach and impact of the Center, and potentially to engage collaborators on research issues relevant to the Center mission and themes. 8) Encourage the involvement of Center investigators in community outreach and education efforts. 9) Prepare and deliver the required reports to the NSF and the NIEHS. 10) Organize COHH meetings as required. 11) Ensure compliance with data submission and archiving policies.

描述（由申请人提供） 该计划项目应用将采用新颖的远程采样技术，以对已知和新出现的 HAB 威胁的种群动态获得新的见解，并解决毒素作用的关键机制，将发育暴露与​​成人后果联系起来。该中心将接受主任和副主任的监督和指导。行政核心的目标是： 1）促进中心成员之间的沟通、规划、整合和互动，从而实现中心的目标和科学目标。 2) 提供并维持一个行政结构来监督和监控中心的财务方面，包括赠款管理。 3) 建立一个结构，通过内部咨询委员会，在所有中心研究人员的贡献下支持有效的沟通和规划。 4) 设立外部咨询委员会，负责审查中心项目并向主任和副主任提供建议。 5) 实施评估机制，利用内部和外部咨询委员会。 6) 建立和维护公共和私人网页，用于信息传播、数据传输和通信 7) 寻求 WHCOHH 与其他 OHH 中心以及其他 EHS 中心之间的互动，以扩大中心的覆盖范围和影响力，并有可能吸引合作者参与与中心使命和主题相关的研究问题。 8) 鼓励中心调查员参与社区外展和教育工作。 9) 准备并向 NSF 和 NIEHS 提交所需的报告。 10) 按要求组织COHH会议。 11) 确保遵守数据提交和归档政策。