Woods Hole Center for Oceans and Human Health

描述（由申请人提供） 本申请的目标是在马萨诸塞州的伍兹霍尔建立一个NIEHS/NSF海洋和人类健康中心。 这将是一个多机构中心，其使命是成为海洋学、生物学和环境卫生科学交叉问题的研究和交流中心，以改善公众健康。 该中心将涉及伍兹霍尔海洋研究所、海洋生物实验室和马萨诸塞州理工学院的调查人员和设施。 伍兹霍尔海洋生物多样性委员会将在包括海湾、港口和河口在内的温带沿海海洋主题区处理可能对人类健康产生影响的生物制剂分布的基本问题。 在这一地理主题范围内，该中心的研究项目将侧重于有害藻华和人类病原体和传染媒介，在这两种情况下，都有重点和互补的物理海洋学研究和病原体的生物学研究。 该中心将包括四个研究项目。 研究项目将与先进的基因组学设施核心相结合，建立一个不寻常的力量组合，并辅以试点项目计划。建议的核心和项目是：项目1。缅因州海湾的亚历山大藻种群生物学，项目2。亚历山大藻种群生物学的流体动力学强迫，项目3。人类病原体和沿海海洋过程，项目4。两种海洋病原菌的微生态与进化基因组学设施核心。

DESCRIPTION (provided by applicant) The goal of this application is to establish an NIEHS/NSF Center for Oceans and Human Health in Woods Hole Massachusetts. This will be a multi-institutional Center, with a mission to be a focal point for research and communication on issues at the intersection of oceanographic, biological and environmental health sciences, to improve the public health. The Center will involve investigators and facilities of the Woods Hole Oceanographic Institution, the Marine Biological Laboratory, and the Massachusetts Institute of Technology. The Woods Hole COHH will address fundamental issues of the distribution of biological agents with potential human health consequences, in the theme area of the temperate coastal ocean, including bays, harbors and estuaries. Within this geographic theme, Research Projects in the Center will focus on harmful algal blooms and on human pathogens and infectious agents, in both cases with focused and complementary physical oceanographic studies and biological studies of causative agents. The Center will comprise four Research Projects. The Research Projects will be coupled with an advanced Genomics Facility Core, establishing a combination of unusual strength, and supplemented by a Pilot Project program. The proposed Cores and Projects are: Project 1. Alexandrium Population Biology in the Gulf of Maine, Project 2. Hydrodynamic Forcing of Alexandrium Population Biology, Project 3. Human Pathogens and Coastal Ocean Processes, Project 4. Microecology and Evolution of Two Marine Pathogens. Genomics Facility Core.