SLEEP DISTURBANCE AND PAIN MODULATION

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。慢性疼痛患者通常伴有睡眠障碍。然而，很少有系统的研究评估疼痛和睡眠之间的相互关系。这项初步研究将评估几种类型的睡眠剥夺对健康女性志愿者疼痛敏感性、疼痛调制和生理/心理症状的影响。这项研究的数据将被用作更大规模的NIH拨款申请的初步研究。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Patients with chronic pain commonly have concomitant sleep disturbance. However, very little systematic research has evaluated the interrelationships between pain and sleep. This pilot study will evaluate the effects of several types of sleep deprivation upon pain sensitivity, pain modulation, and physical/psychological symptoms in healthy female volunteers. Data from this research will be used as preliminary research for a larger scale NIH grant application.