REGULATION OF MUSCLE AND HEPATIC TRIGLYCERIDE AND INSULIN RESISTANCE IN BURNED

本子项目是利用由NIH/NCRR资助的中心赠款提供的资源的众多研究子项目之一。子项目和研究者（PI）可能已经从另一个NIH来源获得了主要资金，因此可以在其他CRISP条目中表示。列出的机构是中心的，不一定是研究者的机构。这项研究的目的是研究为什么烧伤儿童的肝脏中会有大量脂肪，血液中会有高水平的糖。将测试两种新药（普萘洛和非诺贝特），看看它们是否能帮助纠正这些问题。整个研究将在Shriners医院进行除了核磁共振成像。核磁共振成像将用于测量各种治疗后腿部和肝脏内的脂肪量

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to study why children with burns develop large amounts of fat in their liver, and high levels of sugar in their blood. 2 new drugs (Propranolo and fenofibrate) will be tested to see if they can help correct these problems. The entire study will be performed at the Shriners Hospital with the exception of the MRI. The MRI will be used to measure the amount of fat inside the leg and the liver following the various treatments