MENTORING NEUROSCIENCE IN LOUISIANA

描述(由申请者提供)：路易斯安那州立大学HSC领导一个由四人组成的伙伴关系 路易斯安那州的科布雷机构对神经科学的研究。该计划 导演和知名科学家是精选的、非常有前途的 初级教员提出了四个研究项目，这些项目是为 指导的共同目标是建立新的具有国家竞争力的研究。 科学的焦点是神经生物学的一个中心问题：理解 突触可塑性和神经元存活的细胞和分子基础 对澄清神经疾病的病理生理学至关重要，例如： 中风、神经创伤和神经退行性疾病。这是一个多学科的 该项目涉及细胞神经生理学、分子生物学和行为学 神经科学。为支持科布雷项目，核心资源包括 脂质信使和分子的成像、神经化学设备 神经生物学。2至5年的招聘计划进一步有利于 通过积极吸引新的研究人员与机构合作 将在知名神经学家的指导下工作，作为导师。一个 所需的行政核心资金相对较少。具体目标 要达到这些目标是：1)通过以下方式促进教师发展 研究项目；2)进一步发展具有竞争力的临界量 由外部资助的调查人员的招募、启动、指导和 留住新教员；3)加强关键基础设施 通过开发三个核心来扩展路易斯安那州的神经科学能力 LSUHSC的研究模块；4)提供科学和勇气 指导和加强促进互动的支持网络；以及 5)实施中期和结果评估，以保留该Cobre 程序已步入正轨。这种合作关系建立在现有的专业知识和我们公司的基础上。 决定建立一个在科学上成功的神经科学联盟 路易斯安那州。四名目标教员和四名拟招聘教员是 实现这些目标的关键基石。核心资源是 对这个联盟的整体成功至关重要，不仅在神经科学方面，而且 在所有生物医学科学中。指导初级教职员工和 招聘计划将确保源源不断地涌现出具有全国竞争力的新员工 路易斯安那州的神经学家。

DESCRIPTION (provided by applicant): The LSU-HSC leads a partnership of four Louisiana institutions in a COBRE on neuroscience research. The Program Director and established scientists are mentors to selected, highly promising junior faculty who propose four research projects that have been designed for the common goal of mentoring to build new nationally competitive research. The scientific focus is on a central issue of neurobiology: to understand the cellular and molecular basis of synaptic plasticity and neuronal survival critical to clarify the pathophysiology of neurological disorders such as: stroke, neural trauma and neurodegenerative diseases. This multidisciplinary program involves cellular neurophysiology, molecular biology and behavioral neuroscience. To support the COBRE projects, core resources include facilities for imaging , neurochemistry of lipid messengers and molecular neurobiology. A recruitment plan for years 2 to 5 further benefits the collaborating institutions by actively attracting new research faculty who will work under the guidance of established neuroscientists as mentors. A relatively small administrative core funding is requested. The specific aims to attain these objectives are: 1) to promote faculty development through research projects; 2) to further develop a critical mass of competitive extramurally funded investigators by the recruitment, start up, mentoring and retention of new faculty members; 3) to enhance the infrastructure critical for expanding neuroscience capability in Louisiana by developing three core research modules at LSUHSC; 4) to provide scientific and grantsmanship mentoring and strengthen the support network that promotes interactions; and 5) to implement interim and outcome evaluations so as to keep this COBRE program on track. This partnership rests on existing expertise and in our firm decision to build a scientifically successful neuroscience alliance in Louisiana. The four target faculty and the four to-be-recruited faculty are the critical building blocks to achieve these goals. The core resources are vital to the overall success of this consortium, not only in neuroscience but in all the biomedical sciences. The plans for mentoring junior faculty and the recruitment plan will ensure a steady stream of new nationally competitive neuroscientists in Louisiana.