COBRE: LOUISVILLE RES FOUND INC: CORE D: NMR & PROTEIN PURIFICATION FACILITIES

这个子项目是利用由NIH/NCRR资助的中心拨款提供的资源的许多研究子项目之一。子项目和调查员(PI)可能从另一个NIH来源获得了主要资金，因此可能会出现在其他CRISE条目中。列出的机构是针对中心的，而不一定是针对调查员的机构。Core D设施的主要目标是为癌细胞和组织的结构分析和代谢组学提供基础设施和支持，并以高产量生产适合核磁共振分析的蛋白质。这包括稳定的同位素标记策略，包括15N和13C前体。我们的目标仍然是简化数据收集和分析。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The primary aims of the Core D facility are to provide infrastructure and support for structural analysis and metabolomics of cancer cells and tissue, and for producing proteins in high yield suitable for NMR analysis. This includes stable isotope labeling strategies including 15N and 13C precursors. Our goals continue to be to streamline both data collection and analysis.