CTSA INFRASTRUCTURE FOR CLINICAL TRIALS

CTSA 临床试验基础设施

• 批准号: 7328005
• 负责人: ROBERT S SHERWIN
• 金额: $ 158.12万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7328005
• 关键词: bioengineering /biomedical engineering; bioinformatics; clinical research; community; health; medicine; training; university

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Yale Center for Clinical Investigation (YCCI) was created to provide a "home" for training the next generation of clinical investigators. Key programmatic goals are to 1) attract highjy talented students and junior faculty across medicine, nursing, public health, biological sciences and biomedical engineering; and train them in the use of state-of-the-art research tools; give them the skills to work within complex research teams; and support their professional development; and 2) foster the translation of disease-related discoveries from the laboratory into the community by: stimulating the creation of Interdisciplinary teams; making available state-of-the-art core facilities and expanded biostatistical and bioinformatics resources; establishing organizational and regulatory infrastructure for clinical studies; and forging a dynamic new partnership that will integrate community leaders, physicians, and health centers. Participating institutions include the Schools of Medicine, Nursing, Public Health, the Department of Biomedical Engineering and Graduate Programs in Biological and Biomedical Sciences. The Investigative Medicine program (IMP) is central to YCCI's education and training efforts. It is a unique doctoral program that offers Ph.D. degrees in Health Sciences Research to highly qualified M.D. fellows embarking on careers in translational or clinical research. IMP will be expanded with CTSA support to include nursing, public health, biological sciences, and MD-PhD students. YCCI has also created a Society of YCCI Faculty Mentors who will participate actively in the training and nurturing of the students and junior faculty members identified as YCCI Clinical Scholars. Pilot and feasibility (P&F) grants will be awarded for. 1) junior faculty; 2) interdisciplinary translational teams; 3) new technologies; and 4) community-based projects. YCCI will cluster research cores around common themes, including: imaging; specimen analysis; physiology; cognition and behavior; drug development; and cell therapy. A new Office of Research Services will provide facilities for "one-stop" shopping for regulatory, biostatistical, bioinformatics, recruitment and other support services. YCCI will have an office to coordinate the University's efforts to address health issues facing our community. The University's decision to immediately provide substantial support to establish the YCCI reflects its strong commitment to an innovative redesign of our clinical and translational research activities

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子弹和调查员（PI）可能已经从其他NIH来源获得了主要资金，因此可以在其他清晰的条目中代表。列出的机构适用于该中心，这不一定是调查员的机构。耶鲁大学临床调查中心（YCCI）的创建是为了培训下一代临床研究人员的“家”。关键的程序化目标是1）吸引高级才华横溢的学生和跨医学，护理，公共卫生，生物科学和生物医学工程的初级教师；并培训他们使用最先进的研究工具；给他们在复杂的研究团队中工作的技能；并支持他们的专业发展； 2）通过以下方式促进了从实验室向社区的发现转化：刺激跨学科团队的创建；提供最先进的核心设施，并扩大生物统计学和生物信息学资源；建立临床研究的组织和监管基础设施；并建立一个充满活力的新伙伴关系，将整合社区领导者，医师和卫生中心。参与的机构包括医学院，护理，公共卫生，生物医学工程系和生物生物医学科学领域的研究生课程。调查医学计划（IMP）对于YCCI的教育和培训工作至关重要。这是一个独特的博士课程，提供博士学位。卫生科学研究学士学位研究高度合格的医学博士研究员，从事转化或临床研究的职业。 IMP将通过CTSA支持扩展，包括护理，公共卫生，生物科学和MD-PHD学生。 YCCI还建立了一个由YCCI教师的社会，他们将积极参与培训和培养学生和初级教职员工，被确定为YCCI临床学者。将授予飞行员和可行性（P＆F）赠款。 1）初级教师； 2）跨学科的翻译团队； 3）新技术； 4）基于社区的项目。 YCCI将研究核心研究核心，包括：成像；标本分析；生理;认知和行为；药物开发；和细胞疗法。新的研究服务办公室将为“一站式”购物提供监管，生物统计，生物信息学，招聘和其他支持服务的设施。 YCCI将设有一个办公室来协调大学为解决我们社区面临的健康问题所做的努力。大学立即提供大量支持以建立YCCI的决定反映了其对我们临床和转化研究活动的创新重新设计的坚定承诺