Hormonal responsive coding and non-coding genes in penile differentiation and hypospadias
Hormonal responsive coding and non-coding genes in penile differentiation and hypospadias
批准号:
nhmrc : GNT1138950
负责人:
A/Pr Andrew Pask
金额:
$83.52万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
Hypospadias, a failure of the correct formation of the penis, is the second-most common birth defect, occurring in around 1% of boys. It causes distress to both newborn and parents, requiring surgical intervention, and is a burden of cost and is a risk to the child. Furthermore, it is frequently associated with other abnormalities. We have a novel model in which we can induce penis abnormalities and define the link between hormonal exposures and defective penis differentiation.
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