Data Management and Biostatistics Core/Long, Cynthia

数据管理和生物统计核心将支持项目1-3，并协助制定 作为这些项目的结果，对脊柱手法的机制进行了新的、创新性的研究。这个核心 将提供1)数据分析和统计建模、2)数据库应用程序开发以及 3)数据协调与管理。这些领域的专业知识对于成功开展 项目。该中心将为发展研究中心提供生物统计学领导。 脊椎按摩手法的作用机制和效果。这包括为以下项目提供生物统计学支持 对项目1-3中提议的实验进行适当的数据分析和有效解释， 以及参与研究设计、数据分析计划和未来样本量预测 R01和其他因成功完成这些项目而提交的赠款。核心意志 为发展中心的所有方面提供数据协调和管理，包括 负责开发数据收集表单和屏幕，开发基于Web的应用程序以 支持数据和项目管理，并执行数据安全和数据质量控制程序； 存储和备份。将为每个项目定制基于网络的数据管理系统， 满足动物登记、患者登记、治疗分配、数据输入、验证等需求 以及验证、数据编辑和审计。该系统还将允许实时项目报告，以促进 高效有效的项目管理。数据管理和生物统计核心也将促进 项目、核心和内部指导委员会成员之间的数据共享。

The Data Management and Biostatistics Core will support Projects 1 - 3 and assist in the development of new, innovative research on the mechanisms of spinal manipulation as a result of these projects. This core will provide expertise in 1) data analysis and statistical modeling, 2) database application development, and 3) data coordination and management. Expertise in these areas is critical for the successful conduct of projects. The Core will provide biostatistical leadership for the Developmental Center for the Study of Mechanisms and Effects of Chiropractic Manipulation. This includes providing biostatistical support for conducting appropriate data analysis and valid interpretation for the experiments proposed in Projects 1-3, as well as participation in the study design, data analysis plans and sample size projections for the future R01 and other grant submissions resulting from the successful completion of these projects. The Core will provide data coordination and management for all aspects of the Developmental Center, including the responsibility for developing data collection forms and screens, developing web-based applications to support data and project management and executing procedures for data security and data quality control, storage and back-up. The web-based data management systems will be customized for each project, meeting needs such as animal registration, patient enrollment, treatment assignment, data entry, verification and validation, data editing and auditing. The systems will also allow for real-time project reports to facilitate efficient and effective project management. The Data Management and Biostatistics Core will also facilitate data sharing among projects, cores, and Internal Steering Committee Members.