Effect of Spinal Mani on Sensorimotor Func in Back Pain Patients/Meeker, William

脊柱对背痛患者感觉运动功能的影响/Meeker, William

• 批准号: 7280090
• 负责人: JOEL G PICKAR
• 金额: $ 11.71万
• 依托单位: PALMER COLLEGE OF CHIROPRACTIC
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7280090
• 关键词: Address; Affect; Animal Model; Back Pain; Behavior; Biological; Biology; Biomechanics; Caring; Characteristics; Clinical; Clinical Trials; Clinical Trials Design; Collaborations; Data; Defect; Development; Etiology; Functional disorder; Funding; Goals; Guidelines; Health Status; Individual; Iowa; Lead; Light; Low Back Pain; Manuals; Measures; Muscle; NIH Program Announcements; National Center for Complementary and Alternative Medicine; Neurons; Outcome; Pain; Pathway interactions; Patient Self-Report; Patients; Pelvis; Physiological; Positioning Attribute; Posture; Procedures; Public Health; Randomized Controlled Clinical Trials; Range; Research; Review, Systematic (PT); Role; Sensorimotor functions; Source; Space Perception; Spinal; Spinal Manipulation; Subcategory; Subgroup; Symptoms; Time; Tissues; Universities; Variant; Vertebral column; Visit; Week; Work; base; chiropracty; clinical application; clinical effect; disability; dosage; improved; neurophysiology; response; symposium

PROVIDED. Spinal manipulation is a popular and widely used CAM treatment for back pain. It has been shown to be effective in a preponderance of clinical trials, but the reasons why manipulation works are unknown. The long-term goal for this study is to understand the physiological mechanisms of various forms of spinal manipulation in order to refine and improve this therapy for appropriately selected patients. Back pain patients demonstrate deficiencies in sensorimotor function. These may be related to the effects that manipulation appears to have on neurophysiology. Hence, the objective of this study is to assess the effects of high-velocity low-amplitude spinal manipulation(HVLA-SM) and low-velocity variable amplitude spinal manipulation (LVVA-SM) on three types of sensorimotor abilities in patients with low back pain. In collaboration with the University of Iowa, the Palmer Center for Chiropractic Research will pursue the following Specific Aims: 1) To determine the immediate pre-to-post changes from HVLA-SM and LVVA-SM, compared to a no-treatment control, on sensorimotor function as measured by: lumbo-pelvic repositioning ability, standing postural sway, and response to sudden trunk loading; 2) To determine the effects of 2 weeks (4 applications @ 2 per week) of HVLA-SM and LVVA-SM, compared to a no-treatment control, on sensorimotor function as measured by: lumbo-pelvic repositioning ability, standing postural sway, and response to sudden trunk loading; 3) To determine the effects of 6 weeks (12 applications @ 2 per week) of HVLA-SM and LVVA-SM on sensorimotor function as measured by: lumbo-pelvic repositioning ability, standing postural sway, and response to sudden trunk loading; 4) To explore whether changes in sensorimotor function are associated with changes in self-reported back pain intensity, related disability, or health status at 2 weeks (after 4 SM Visits) and at 6 weeks (after 12 SM Visits); and 5) To determine if sensorimotor function changes are greater in patients clinically classified as being most appropriate for manipulation. If spinal manipulation is demontrated to improve the sensorimotor functions of back pain patients and correlate with improvements in clinical symptoms and related disability, it will further define the appropriate clinical role of this CAM treatment, potentially enhance understanding about the etiology of back pain, and lead to improved treatment for a costly and common public health problem.

但前提是。 脊柱手法是治疗背部疼痛的一种流行和广泛使用的CAM治疗方法。它已经被证明是 在大多数临床试验中有效，但手法奏效的原因尚不清楚。这个 这项研究的长期目标是了解各种形式的脊柱的生理机制。 手法，以便为适当选择的患者改进和改进这一治疗方法。背部疼痛 患者表现出感觉运动功能的缺陷。这些可能与以下效应有关 手法似乎对神经生理学有影响。因此，这项研究的目的是评估 高速低幅脊柱手法(HVLA-SM)和低速可变幅度脊柱手法 手法疗法对下腰痛患者三种感觉运动能力的影响在……里面 与爱荷华大学合作，帕尔默脊椎疗法研究中心将致力于 具体目标如下：1)确定HVLA-SM和LVVA-SM在实施前后的即时变化； 与未经治疗的对照组相比，对感觉运动功能的影响通过测量：腰盆重新定位 能力、站立姿势摆动和对躯干突然负荷的反应；2)确定2周的效果 (4次应用，每周2次)，与不治疗对照相比， 感觉运动功能通过：腰盆重新定位能力，站立姿势摆动，以及 对树干突然负荷的反应；3)确定6周(12次应用，每周2次)的效果 HVLA-SM和LVVA-SM对感觉运动功能的影响：腰盆定位能力， 站立姿势摆动和对躯干突然负荷的反应；4)探讨 感觉运动功能与自我报告的背痛强度、相关残疾或 2周(4次SM访问后)和6周(12次SM访问后)的健康状况；以及5)确定 感觉运动功能变化较大的患者被临床归类为最适合 操纵。如果脊柱手法被证明能改善背痛的感觉运动功能 并与临床症状和相关残疾的改善相关，它将进一步定义 这种CAM治疗的适当临床作用，潜在地增强了对背部病因的理解 疼痛，并导致改善对一个昂贵和常见的公共卫生问题的治疗。