Immersion in Drug Abuse

沉浸在药物滥用中

• 批准号: 7632991
• 负责人: ESTELLE B. GAUDA
• 金额: $ 1.87万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7632991
• 关键词: Adolescence; Adolescent Medicine; Adverse effects; Age; Behavior; Biology; Birth; Brain; Development; Doctor of Medicine; Doctor of Philosophy; Drug Addiction; Drug Metabolic Detoxication; Drug abuse; Drug usage; Education; Family; Fetus; Goals; Grant; Human; Illicit Drugs; Immersion Investigative Technique; Intervention; Learning; Mediating; Medical Students; Medical center; Mission; NIH Program Announcements; National Institute of Drug Abuse; Newborn Infant; Opiate Addiction; Opiates; Patient currently pregnant; Pharmaceutical Preparations; Physicians; Pregnancy; Pregnant Women; Prevention strategy; Reporting; Research; Research Personnel; Research Training; Risk-Taking; Scientist; Staging; Students; Surveys; Training; Training Programs; United States; Universities; Week; Woman; addiction; base; career; design; experience; fetal; nervous system development; next generation; novel; pediatric department; programs; psychosocial; reproductive; response

A NIDA conducted national survey reported that 5.5% of 4 million women who gave birth in the United States in 1992 used illegal drugs while they were pregnant. In addition to the psychosocial ramifications, illicit drug use also has adverse effects on the development of the nervous system in the fetus and newborn and increases the possibilities of risk taking behavior in adolescence. Little is known about the biology of addiction to illicit drugs in the developing fetus and newborn and few investigators specialize in this important field. In response to the program announcement (PAR-04-054), Research Education Grants in Drug Abuse and Addiction, the overall goal of this proposal is to bring together the scientific and educational expertise in drug abuse research at Johns Hopkins and Morgan State University to create a novel educational/research training program with the mission of training researchers in the basic biology and psychosocial aspects of illicit drug use in the young woman entering reproductive age, the pregnant woman, and her fetus and newborn. Under the co-directorship of Estelle Gauda, M.D., a physician-scientist at Johns Hopkins, and Gabrielle McLemore, Ph.D., a educator-scientist at Morgan State University, we have created a partnership between investigators from the Center for Addiction and Pregnancy at Johns Hopkins Bayview Medical Center, the Kennedy Krieger Family Center, the Department of Pediatrics and Adolescent Medicine at Johns Hopkins University, and Morgan State University to accomplish this goal through 2 educational programs. The Summer Immersion in Drug Abuse Research Program (SIDARP) is a 10 week educational-research/training experience which will target doctoral students, medical students, and physicians at an early stage of their professional careers. The Drug Abuse Research Training (DART) Program is a long-term (2-3 years) research experience designed to target pre and postdoctoral students and clinician-scientists to be the next generation of leaders in the field of drug addiction and abuse research and education. The training program will use a competency based learning strategy to maximize learning. Emphasis will be given to having educational and research opportunities that will include basic mechanisms mediating drug dependence and tolerance in the fetus and newborn, effects of opiate exposure on human fetal behavior and newborn brain development, alternative treatment and detoxification strategies for opiate addiction during pregnancy and in the newborn, and drug abuse intervention and prevention strategies in women of reproductive age.

NIDA进行的一项全国性调查报告称，在美国400万名分娩的妇女中，有5.5%的人 1992年，她们在怀孕期间服用非法药物。除了心理社会影响之外，非法药物 使用还会对胎儿和新生儿的神经系统发育产生不利影响 增加了青春期冒险行为的可能性。对其生物学知识知之甚少。 发育中的胎儿和新生儿对非法药物的依赖，很少有研究人员专门研究这一重要的 菲尔德。为回应计划的公布(PAR-04-054)，药物滥用研究教育补助金 和成瘾，这项建议的总体目标是将科学和教育结合起来 约翰·霍普金斯大学和摩根州立大学在药物滥用研究方面的专业知识创造了一部小说 以培养基础生物学研究人员为使命的教育/科研培训计划 在进入生育年龄的年轻女性中，非法药物使用的心理社会方面， 孕妇，以及她的胎儿和新生儿。在埃斯特尔·高达医学博士联席董事的领导下， 约翰·霍普金斯大学的内科医生兼科学家，以及摩根州立大学的教育家兼科学家加布里埃尔·麦克勒莫尔博士 大学，我们已经在成瘾中心的调查人员和 约翰·霍普金斯湾景医疗中心肯尼迪·克里格家庭中心 约翰霍普金斯大学和摩根州立大学的儿科和青少年医学专业 通过2个教育项目实现这一目标。药物滥用研究中的夏日沉浸 计划(SIDARP)是一个为期10周的教育研究/培训经验，目标是博士 学生、医学生和医生在其职业生涯的早期阶段。药物滥用 研究培训(DART)计划是一项长期(2-3年)的研究经验，旨在面向Pre 博士后和临床医生科学家将成为药物领域的下一代领导者 成瘾和滥用研究和教育。培训计划将使用基于能力的学习 最大化学习的策略。将重点放在有以下教育和研究机会上 将包括调节胎儿和新生儿药物依赖和耐受性的基本机制，影响 阿片类药物暴露对胎儿行为和新生儿大脑发育的影响、替代治疗和 孕期和新生儿阿片成瘾和药物滥用的戒毒策略 育龄妇女的干预和预防策略。