Design Specifications of Brain-Controlled Neuroprostheses

描述(申请人提供)：本提案寻求赞助一个为期2天的研讨会，该研讨会将汇集来自不同学科的专家，为脑控康复系统制定共识设计规范，例如基于功能性电刺激(FES)的神经假体，用于恢复患有神经疾病(如颈椎脊髓损伤(SCI)和中风)的个人的上肢运动控制。研讨会的目标是确定阻碍在临床部署的康复系统中使用脑机接口(BMI)的科学和技术挑战，并提出解决这些挑战的未来研究活动建议。我们将汇集来自几个不同研究领域的专家(包括自然和人工控制系统、与BMI相关的神经科学、植入的BMI设备和临床应用)，这些领域的专家通常不会相互作用，但他们的技能和洞察力是开发临床相关BMI的综合方法所必需的。拟议的研讨会将包括各种研究领域公认的专家的简要报告，以及这些专家提出的个别主题的充分讨论。研讨会参与者将被分成五个不同的任务组，以确定不同领域的挑战和建议方法：(1)外周运动控制考虑因素，(2)可用BMI信号的来源和特性，(3)从BMI信号中提取相关的运动控制信息，(4)实用BMI设备，以及(5)BMI的临床应用。任务组将被要求确定战略研究领域，以便在未来1年、5年和10年内将BMI逐步转移到更复杂的临床应用中。这些讨论和建议的摘要报告将在会后提供给NINDS，并在适当的期刊上发表。与公共健康相关：该提案寻求对一个为期两天的研讨会的赞助，该研讨会将汇集来自一系列学科的专家，以制定大脑控制康复系统的共识设计规范。其目标是确定阻碍脑机接口(BMI)在临床上部署的康复系统中使用的科学和技术挑战，并提出解决这些挑战的未来研究活动建议。这些讨论和建议的摘要报告将在会后提供给NINDS，并在适当的期刊上发表。

DESCRIPTION (provided by applicant): This proposal seeks sponsorship for a 2 day workshop that will pull together experts from a range of disciplines to develop consensus design specifications for brain controlled rehabilitation systems such as functional electrical stimulation (FES)-based neuroprostheses for restoring upper extremity movement control to individuals with neurological disorders such as cervical spinal cord injury (SCI) and stroke. The goals of the workshop are to identify scientific and technological challenges that hinder the use of brain-machine interfaces (BMI) in clinically deployed rehabilitation systems and to suggest future research activities that would address these challenges. We will bring together experts from several different research areas (both natural and artificial control systems, neuroscience related to BMI, implanted BMI devices, and clinical applications) that may not typically interact but whose skills and insight are needed to develop an integrated approach to clinically relevant BMI's. The proposed workshop will include brief presentations by acknowledged experts in the various research areas and ample discussion on the individual topics presented by these experts. Workshop participants will be divided into five different Task Groups to identify challenges and suggest approaches in different areas: (1) Peripheral motor control considerations, (2) Sources and properties of available BMI signals, (3) Extraction of relevant movement control information from BMI signals, (4) Practical BMI devices, and (5) Clinical applications of BMI. The Task Groups will be asked to identify strategic research areas for moving BMI's into incrementally more sophisticated clinical applications over the next 1, 5, and 10 years. A summary report of these discussions and recommendations will be provided to NINDS following the meeting and published in an appropriate journal. PUBLIC HEALTH RELEVANCE: This proposal seeks sponsorship for a 2 day workshop that will pull together experts from a range of disciplines to develop consensus design specifications for brain controlled rehabilitation systems. The goals are to identify scientific and technological challenges that hinder the use of brain-machine interfaces (BMI) in clinically-deployed rehabilitation systems and to suggest future research activities that would address these challenges. A summary report of these discussions and recommendations will be provided to NINDS following the meeting and published in an appropriate journal.