Center for Clinical and Translational Sciences

德克萨斯大学休斯顿健康科学中心(UTHSC-H)建议建立一个 位于德克萨斯州休斯敦的德克萨斯医学中心(TMC)的临床和转化科学(CCTS)。 参加CCTS的教员和实习生将包括UTHSC-H组成部分学位的教师和实习生 授予学校，包括其医学院、公共卫生学院、生物医学研究生院 理科、健康信息科学学院、护理学院、牙科学院和 分子医学(IMM)，以及来自德克萨斯大学安德森癌症医学中心的合作学院/设施 中心(MDACC)，也位于TMC。中国计算机科学研究院的学术“家”将被定位 在犹他州大学医学院11,422平方英尺的新装修和CCTS指定空间中， 实际加入赫尔曼纪念医院(MHH)，担任其合作伙伴和主要教学 医院。CCTS“总部”将管理CCTS的方方面面，并为 教职员工和受训人员，以及研究设计、生物统计学、监管问题、伦理和 生物信息学，为试点和可行性研究提供资金，提供资源和保护时间 临床和翻译教师和实习生以及与不同社区的互动/合作 和工业。对于参与者和临床互动资源(PCIR)，CCTS将包含 位于MHH的UTHSC-H综合临床研究中心(GCRC)，位于布朗斯维尔的卫星UTHSC-H GCRC， 德克萨斯州，以及部分MDACC临床和翻译研究中心，以加强研究 生产力和效率。在其教育组成部分中，CCTS将部分地包括目前的 临床研究和循证医学中心，已经开发并目前提供 UTHSC-H的正式课程、指导和临床研究(MCR)硕士学位，以及活跃的 NCRR K30奖在MDACC。应用程序中还提出了一种新的T32应用程序产品 社区卫生科学、生物医学科学和/或硕士和博士学位的结合 生物医学信息学，主要面向博士后学生，K12应用于博士后实习生 和初级教员。CCTS还将纳入核心翻译实验室，包括 基因分型/测序Corel是提供DNA微阵列、RT-PCR和蛋白质组学的生物标志物核心 服务，免疫监测核心，核磁共振成像核心，和生物库核心。CCTS的“智库” 由高水平的翻译和临床研究人员、基础科学家和教育工作者组成，以及 社区代表将汇聚一堂，作为创新的引擎，推动和 推荐应用新出现的科学信息、方法和技术 跨专业、学科和社区研究人类健康和疾病。。

The University of Texas Health Science Center at Houston (UTHSC-H) proposes to establish a Center for Clinical and Translational Sciences (CCTS) in the Texas Medical Center (TMC), Houston, Texas. Participating faculty and trainees in the CCTS will include those from the UTHSC-H component degree granting schools, including its School of Medicine, School of Public Health, Graduate School of Biomedical Sciences, School of Health Information Sciences, School of Nursing, Dental School and Institute of Molecular Medicine (IMM), as well as collaborating faculty/facilities from the UT M.D. Anderson Cancer Center (MDACC) and which also is located in the TMC. The academic "home" for the CCTS will be located in 11,422 sq ft of newly renovated and CCTS-designated space at the UTH Medical School which is physically joined to the Memorial Hermann Hospital (MHH) and serves as its partner and major teaching hospital. The CCTS "home" will administer all aspects of the CCTS and provide space and resources for faculty and trainees, along with expertise in study design, biostatistics, regulatory issues, ethics, and bioinformatics, and funding of Pilot and Feasibility Studies, provision of resources and protected time for clinical and translational faculty and trainees and interactions/collaborations with the various communites and industry. For Participant and Clinical Interactions Resources(PCIR), the CCTS will subsume the UTHSC-H General Clinical Research Center (GCRC) at MHH, the satellite UTHSC-H GCRC at Brownsville, Texas, and, in part, the MDACC Clinical and Translational Research Center to enhance research productivity and efficiency. In its Educational Component, the CCTS will subsume, in part, the current Center for Clinical Researchand Evidence-Based Medicine, which has developed and currently provides formal classes, mentoring, and a Masters Degree in Clinical Research (MCR) at UTHSC-H, and an active NCRR K30 award at MDACC. Also proposed in the application is a novel T32 application offering combinations of Masters and PhD degrees in Community Health Sciences,'Biomedical Sciences and/or Biomedical Informatics, primarily for pre-doctoral students, and a K12 application for post-doctoral trainees andjunior faculty. The CCTS also will subsume Core Translational Laboratories, including a enotyping/Sequencing Corel a Biomarkers Core offering DNA Microarray, RT-PCR and Proteomics services , an Immune Monitoring Core, an MRI Imaging Core, and a Biobanking Core. A CCTS "Think Tank" comprised of highly accomplished translational and clinical Investigators, basic scientists and educators, and community representatives,will come together as an "engine for innovation" to bring forward and recommend the application of novel and emerging scientific information, methods and technologiesto research into human health and diseases across specialties, disciplines and communities. .