Portable Liquid-Fueled Catalytic Heater for Infusion Fluids

用于输液的便携式液体燃料催化加热器

• 批准号: 7537979
• 负责人: LINDA A TEMPELMAN
• 金额: $ 14.41万
• 依托单位: GINER, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2009-08-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7537979
• 关键词: Air; Anesthesia procedures; Area; Arts; Blood; Body Temperature; Caring; Cells; Charge; Complex; Computer Simulation; Condition; Construction Materials; Coupling; Developed Countries; Developing Countries; Development; Devices; Disasters; Distant; Economics; Emergency Situation; Emergency treatment; Engineering; Equipment; Erythrocytes; Generations; Goals; Heating; Hemorrhage; Hour; Hurricane; IV Fluid; Infusion procedures; Life; Liquid substance; Mechanics; Medical; Medical Device; Membrane; Methanol; Methods; Military Medicine; Military Personnel; Modeling; Monitor; Numbers; Operative Surgical Procedures; Outcome; Oxygen; Patient Care; Patients; Permeability; Phase; Physicians; Process; Property; Public Health; Range; Rate; Reaction; Research; Research Infrastructure; Services; Shock; Side; Solutions; Structure; Surface; System; Technology; Temperature; Testing; Transmembrane Transport; Trauma; Universities; aqueous; base; catalyst; commercial application; cost; crystalloid; design; energy balance; heat exchanger; improved; innovation; intravenous administration; medical schools; milliliter; natural hypothermia; oxidation; programs; prototype; research study; size; stem; treatment site; vapor

DESCRIPTION (provided by applicant): Portable Liquid-Fueled Catalytic Heater for Infusion Fluids The overall objective of this project is to develop a lightweight, portable, low-cost device powered by liquid fuel for warming intravenous fluids in-the-field distant from medical infrastructure. Excessive hemorrhage, hypothermia and the accompanying shock are among the emergency conditions that often require timely intravenous infusion of large volumes of warmed infusion fluids such as crystalloid or packed red cells. On-site treatment of trauma victims with warmed, intravenous fluids during the critical first hour after the onset of a medical emergency requires effective portable equipment that is not yet available. The portable intravenous fluid warmer would be used in: remote areas, disasters such as hurricanes or terrorist attacks, developing countries, and field military medicine. The major innovation of this project is development of a reusable, portable heater for infusion fluids that uses a non-flammable liquid fuel to provide heating capacity for the full range of trauma treatment in disaster situations. Existing portable technology, powered by batteries, lacks sufficient energy to heat the high volumetric flow rate infusions (up to 500 milliters/minute) needed in trauma treatment. This Phase I project will demonstrate feasibility of a design for a liquid-fueled catalytic heater for warming 60 units of refrigerated infusion fluids (for treating up to 20 patients) using one 500-mL fuel cartridge. The Phase I project will include development of a controlled method for supplying liquid fuel to a catalytic heater, design of the catalytic heater hardware, and integration of the catalytic heater with a medical cartridge-type heat exchanger, culminating in demonstration of a breadboard system for heating refrigerated infusion solutions. A preliminary design for an advanced prototype system will be developed and analyzed to determine the technical and economic feasibility of the device for commercial applications. In Phase II, the advanced design will be implemented and extensively tested to provide a prototype device leading to a commercial product. Commercial Potential: There is a large need for portable, self-powered medical devices for emergency treatment in disaster situations, such as hurricanes or terrorist attacks, and in remote areas. The military also has a great need for emergency equipment for field medical treatment. The proposed device would have high commercial potential since it would have widespread applicability for emergency treatment and would be low-cost and have a long service life. PUBLIC HEALTH RELEVANCE: The overall objective of this project is to develop a lightweight, portable, low-cost intravenous fluid warming device powered by liquid fuel for in-the-field medical care more than one hour distant from medical infrastructure. Excessive hemorrhage, hypothermia and the accompanying shock state are among the emergency conditions that often demand timely intravenous infusion of large volumes of warmed infusion fluids such as crystalloid or packed red cells. This portable, intravenous fluid warmer would significantly improve emergency patient care and outcomes in remote areas, disasters such as hurricanes or terrorist attacks, developing countries, and field military medicine.

描述（由申请人提供）：用于输液液的便携式液体燃料催化加热器该项目的总体目标是开发一种由液体燃料提供动力的轻质，便携式，低成本的设备，用于使静脉注射液体远离医疗基础设施。过度出血，体温过低和伴随的休克是紧急情况，通常需要及时静脉内注入大量温暖的输注液，例如结晶或包装的红细胞。在医疗紧急事件开始后的关键第一小时，对创伤受害者的现场治疗需要有效的便携式设备。便携式静脉输液温暖器将用于：偏远地区，飓风或恐怖袭击等灾难，发展中国家和现场军事医学。该项目的主要创新是开发可重复使用的便携式加热器，用于输注液，该加热器使用非易燃的液体燃料为在灾难情况下的全部创伤治疗提供加热能力。现有的便携式技术由电池提供动力，缺乏足够的能量来加热创伤治疗中所需的高容量流量输注（最多500毫米/分钟）。该阶段I项目将证明使用一个500-mL燃料弹药筒为液体燃料催化加热器设计的设计可行性。第一阶段项目将包括开发一种用于催化加热器的液体燃料，催化加热器硬件的设计，以及将催化加热器与医用墨盒型热交换器的集成，最终导致的面包板系统，以表现出用于加热冷冻输液解决方案的面包板系统。将开发和分析针对先进原型系统的初步设计，以确定该设备用于商业应用的技术和经济可行性。在第二阶段，将实施和广泛测试高级设计，以提供通往商业产品的原型设备。商业潜力：在灾难情况（例如飓风或恐怖袭击）和偏远地区，需要便携式，自动医疗设备来进行紧急治疗。军方还非常需要紧急设备进行现场医疗。拟议的设备将具有很高的商业潜力，因为它将广泛适用于紧急治疗，并且将是低成本且使用寿命长。公共卫生相关性：该项目的总体目标是开发一种由液体燃料提供动力的轻质，便携式，低成本的静脉输液升温装置，可用于远离医疗基础设施一小时以上的现场医疗服务。过度出血，体温过低和伴随的休克状态是紧急情况，通常要求及时静脉注射大量温暖的输注液，例如结晶或包装的红细胞。这种便携式，静脉输液的温暖器将显着改善偏远地区的急诊患者护理和结果，例如飓风或恐怖袭击，发展中国家和现场军事医学。