Economical, No-Maintenance, Wearable Alcohol Sensor for Treatment, Research and Consumer Users

适用于治疗、研究和消费者用户的经济型、免维护、可穿戴式酒精传感器

• 批准号: 9050243
• 负责人: LINDA A TEMPELMAN
• 金额: $ 22.49万
• 依托单位: GINER, INC.
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-25 至 2017-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9050243
• 关键词: Alcohol consumption; Alcohols; Ankle; Area; Atrial Fibrillation; Behavioral; Biological Assay; Blood alcohol level measurement; Cause of Death; Cellular Phone; Cessation of life; Clinical; Clinical Research; Criminal Justice; Development; Devices; Diffuse; Effectiveness; Elements; Enzymes; Event; Feasibility Studies; Freedom; Genetic Predisposition to Disease; Goals; Health; Hydration status; Laboratories; Law Enforcement; Location; Maintenance; Manufacturer Name; Marketing; Measures; Memory; Methods; Monitor; Morphologic artifacts; Output; Patient Self-Report; Patients; Performance; Phase; Physiological; Post-Traumatic Stress Disorders; Price; Race; Rehabilitation therapy; Reporting; Research; Signal Transduction; Skin; Solutions; Techniques; Technology; Testing; Time; Veterans; Water; Woman; alcohol abuse therapy; alcohol measurement; alcohol monitoring; binge drinking; commercialization; cost; data exchange; design; drinking; economic cost; improved; innovation; meetings; operation; parole; prevent; public health relevance; research clinical testing; research study; sensor; temporal measurement; treatment program; university student; user-friendly

 DESCRIPTION (provided by applicant): Economical, No aintenance, Wearable Alcohol Sensor for Treatment, Research and Consumer Users Alcohol use remains the third leading cause of death both in the US (85,000 deaths annually) and worldwide (up to 2.5 million deaths annually) with economic costs exceeding $223 billion annually in the US alone. While on-going clinical studies continue to advance the understanding of the behavioral and physiological effects of alcohol use, many of these studies suffer from the lack of a continuous, quantitative, and real-time measurement of alcohol blood levels. Many clinical studies primarily rely on subject self-report of alcohol use, which is severely limited by the inability to accurately quantitate blood alcohol levels, intentional or unintentional misrepresentation, reporting biases, and memory artifacts. Other methods that provide an objective measurement of alcohol, such as biological assays and breathalyzers, also suffer from significant limitations, including invasiveness, constant user interaction, and/or the inability to provide real-time quantitative measurements of alcohol. By contrast, the Giner transdermal alcohol sensor (i.e., WrisTAS(tm) device) provides a noninvasive, continuous, and user-friendly device for measuring alcohol that diffuses through the skin, which is then correlated to blood alcohol levels. The Giner technology is in commercial use for the criminal justice/law enforcement market as an ankle bracelet. However, the major obstacles to a more economical and consumer-friendly device are the substantial labor required to manufacture the alcohol sensing element and the maintenance requirement to refill the water reservoir. Therefore, Giner has proposed innovative solutions to both these obstacles through the development of a new "no maintenance" (i.e., no water refill) device, as well as alternative manufacturing techniques that will enable high-output, roll-to-roll manufacturing designed to reduce assembly time and labor by 80%. With the proposed innovations for the alcohol sensing element used in the WrisTAS(tm) Device, Giner will enable a new version of the transdermal alcohol sensor costing ~$99, thus expanding the use further in clinical research, as well as currently untapped markets, such as the alcohol treatment/rehabilitation, professional monitoring (e.g. pilots, truck drivers, doctors, etc.), and he consumer markets.