The University of Pittsburgh's Comparative Effectiveness Research Scholars Progra

匹兹堡大学比较有效性研究学者计划

• 批准号: 8016138
• 负责人: WISHWA N KAPOOR
• 金额: $ 194.77万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8016138
• 关键词: University; Pittsburgh; Comparative; Effectiveness; Research

DESCRIPTION (provided by applicant): We propose to develop an early career development program involving clinical researchers from the six Schools of the Health Sciences at the University of Pittsburgh and UPMC. Pitt's Comparative Effectiveness Research (CER) Scholars Program is designed to prepare scientists for independent careers in CER. The CER Scholars will receive didactic training and experience in diverse types of research methods to answer questions about the comparative effectiveness of treatments, interventions, and management strategies using cutting-edge research designs and methods. The objectives of the program are to: 1) Provide rigorous didactic training encompassing a broad spectrum of CER research methodologies, technologies, concepts, and research tools; 2) Immerse CER Scholars in multidisciplinary research programs and provide teaching in leadership, management, and team building; 3) Provide mentoring and career guidance to CER Scholars and experiences in the conduct of CER projects from conceptualization to completion; and 4) Guide CER Scholars in the development and submission of competitive grant applications, so they become successful independent researchers. Key features of our program for the development of leaders in CER include: a customized education and training program to meet the needs of individual Scholars (building on courses in development using an ARRA supplement to create a core CER curriculum within the CTSI); excellent training in a diverse set of fundamental skills in CER; a CER-rich research environment of Institutes and centers focusing on lOM priority areas and carrying out diverse CER projects; the opportunity to conduct all aspects of in-depth mentored research projects; experiences participating in an advanced journal club that contributes to Scholars' growth and leadership abilities; opportunities for exploring specific research methods through short-term internships and rotations at evidence-based practice centers; and a multifaceted mentoring program to train both mentees and mentors in how to get the most out of mentoring. The entire training program and all its components will be intensively evaluated. The ultimate goal of the program is to increase the nation's CER capacity. PUBLIC HEALTH RELEVANCE: At a time when rapid advances and new discoveries contribute to the complexity of decision making in health care and health care delivery, the need for excellent comparative effectiveness research is clear. To ensure that the research is of high quality, it is necessary to train a new cohort of investigators in specific CER methods.

描述（由申请人提供）：我们建议制定一项早期职业发展计划，涉及来自匹兹堡大学和 UPMC 六个健康科学学院的临床研究人员。皮特的比较有效性研究 (CER) 学者计划旨在帮助科学家为 CER 的独立职业做好准备。 CER 学者将接受不同类型研究方法的教学培训和经验，以使用尖端研究设计和方法回答有关治疗、干预和管理策略的比较有效性的问题。该计划的目标是： 1) 提供严格的教学培训，涵盖广泛的 CER 研究方法、技术、概念和研究工具； 2) 让 CER 学者参与多学科研究项目，并提供领导力、管理和团队建设方面的教学； 3) 为CER学者提供指导和职业指导，并提供CER项目从概念到完成的实施过程中的经验； 4) 指导 CER 学者制定和提交竞争性资助申请，使他们成为成功的独立研究人员。我们的 CER 领导者发展计划的主要特点包括： 定制的教育和培训计划，以满足个别学者的需求（以开发课程为基础，使用 ARRA 补充在 CTSI 内创建核心 CER 课程）； CER 各种基本技能的出色培训；研究所和中心拥有丰富的 CER 研究环境，重点关注 LOM 优先领域并开展各种 CER 项目；有机会进行深入指导研究项目的各个方面；参与高级期刊俱乐部的经验，有助于学者的成长和领导能力；通过在循证实践中心的短期实习和轮换探索具体研究方法的机会；以及多方面的指导计划，培训学员和导师如何充分利用指导。整个培训计划及其所有组成部分都将得到深入评估。该计划的最终目标是提高国家的核证减排量（CER）容量。 公共卫生相关性：在快速进步和新发现导致医疗保健和医疗保健提供决策变得复杂的时代，显然需要出色的比较效果研究。为了确保研究的高质量，有必要培训一批新的研究人员使用特定的 CER 方法。

项目成果

Consensus recommendations for systematic evaluation of drug-drug interaction evidence for clinical decision support.

• DOI: 10.1007/s40264-014-0262-8
• 发表时间: 2015-02
• 期刊: Drug safety
• 影响因子: 4.2
• 作者: Scheife RT;Hines LE;Boyce RD;Chung SP;Momper JD;Sommer CD;Abernethy DR;Horn JR;Sklar SJ;Wong SK;Jones G;Brown ML;Grizzle AJ;Comes S;Wilkins TL;Borst C;Wittie MA;Malone DC
• 通讯作者: Malone DC

Effectiveness of late gadolinium enhancement to improve outcomes prediction in patients referred for cardiovascular magnetic resonance after echocardiography.

晚期钆增强对改善超声心动图后转诊进行心血管磁共振的患者的结果预测的有效性。

• DOI: 10.1186/1532-429x-15-6
• 发表时间: 2013
• 期刊: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
• 作者: Wong,TimothyC;Piehler,Kayla;Puntil,KathyS;Moguillansky,Diego;Meier,ChristopherG;Lacomis,JoanM;Kellman,Peter;Cook,StephenC;Schwartzman,DavidS;Simon,MarcA;Mulukutla,SureshR;Schelbert,ErikB
• 通讯作者: Schelbert,ErikB

Toward a complete dataset of drug-drug interaction information from publicly available sources.

• DOI: 10.1016/j.jbi.2015.04.006
• 发表时间: 2015-06
• 期刊: JOURNAL OF BIOMEDICAL INFORMATICS
• 影响因子: 4.5
• 作者: Ayvaz, Serkan;Horn, John;Hassanzadeh, Oktie;Zhu, Qian;Stan, Johann;Tatonetti, Nicholas P.;Vilar, Santiago;Brochhausen, Mathias;Samwald, Matthias;Rastegar-Mojarad, Majid;Dumontier, Michel;Boyce, Richard D.
• 通讯作者: Boyce, Richard D.

Automated Communication Tools and Computer-Based Medication Reconciliation to Decrease Hospital Discharge Medication Errors.

自动通信工具和基于计算机的药物协调可减少出院用药错误。

• DOI: 10.1177/1062860615574327
• 发表时间: 2016
• 期刊: American journal of medical quality : the official journal of the American College of Medical Quality
• 作者: Smith,KennethJ;Handler,StevenM;Kapoor,WishwaN;Martich,GDaniel;Reddy,VivekK;Clark,Sunday
• 通讯作者: Clark,Sunday

Medication Treatment of Active Opioid Use Disorder in Veterans With Cirrhosis.

• DOI: 10.14309/ajg.0000000000001228
• 发表时间: 2021-07-01
• 期刊: The American journal of gastroenterology
• 作者: Rogal S;Youk A;Agbalajobi O;Zhang H;Gellad W;Fine MJ;Belperio P;Morgan T;Good CB;Kraemer K
• 通讯作者: Kraemer K