EARLY-ONSET SEPSIS AN NICHD/CDC SURVEILLANCE STUDY

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这是一项前瞻性队列研究。在网络中心出生的婴儿被诊断为早发性脓毒症和/或脑膜炎的队列将得到深入跟踪。 目标是： 1.在产中使用抗生素预防的时代，建立足月儿和早产儿的EOS在医院的现有比率。 2.监测所有出生体重和胎龄的新生儿中与EOS和脑膜炎有关的微生物。 3.比较无症状儿和有症状儿的胎龄和病原体。 4.按病原菌分组监测EOS婴儿败血症相关死亡率。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This is a prospective cohort study. The cohort of infants born at Network centers who are diagnosed to have early-onset sepsis and/or meningitis will be followed indepth. Aims are to: 1. To establish current hospital-based rates of EOS among term and preterm infants in the era of intrapartum antibiotic prophylaxis. 2. To monitor the organisms associated with EOS and meningitis in neonates of all birthweights and gestational ages. 3. To compare asymptomatic and symptomatic infants by gestational age and pathogen. 4. To monitor sepsis-associated mortality rates for infants with EOS, by pathogen group.