FINDING GENES UNDERLYING HUMAN DISEASE

寻找人类疾病的基因

• 批准号: 7956502
• 负责人: Catherine Marie Stein
• 金额: $ 0.48万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7956502
• 关键词: Computer Retrieval of Information on Scientific Projects Database; Development; Funding; Genes; Grant; Human Genetics; Institution; Maps; Methodology; Research; Research Personnel; Resources; Source; Surveys; United States National Institutes of Health; genetic analysis; genome wide association study; human disease

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. With the surge in genome-wide association studies (GWAS), many have asked the question 'Are linkage studies dead?' In this article, we survey the approaches used in mapping human disease genes, reviewing the analysis strategies that preceded and laid the groundwork for GWAS. We note that earlier approaches are still useful and the development of new methodology is warranted.

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