IL-11 as a novel parietal cell cytokine that blocks gastric acid secretion and causes gastric atrophy

IL-11作为一种新型壁细胞细胞因子，可阻断胃酸分泌并导致胃萎缩

• 批准号: nhmrc : 1006688
• 负责人: Dr Louise Judd
• 金额: $ 35万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2013-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/il-11-novel-gastric-atrophy/109206
• 关键词: IL; 11; novel; parietal; cell

Stomach cancer will kill a million people in the world in 2010, while in the western world the numbers of affectd indiviuduals are decreasing while in the in the developing world the opposite is the thus adding to the global health burden. Gastric atrophy is a pathological condition that always preceeds gastric cancer. This project aims to devlop our knowledge of the intitating events that allow atrophy to develop, thus informing us of novel ways of treating this condition before it bcomes cancerous.

2010年，胃癌将在世界上杀死100万人，而在西方世界，受影响的个人人数正在减少，而在发展中国家，情况正好相反，从而增加了全球健康负担。摘要胃萎缩是胃癌发生前的一种病理状态。该项目旨在发展我们对导致萎缩发展的初始事件的知识，从而告知我们在癌变之前治疗这种疾病的新方法。