Tumour associated macrophages and the IL-6 family of cytokines in the progression to gastric cancer

肿瘤相关巨噬细胞和 IL-6 细胞因子家族在胃癌进展中的作用

• 批准号: nhmrc : 509165
• 负责人: Dr Louise Judd
• 金额: $ 34.85万
• 依托单位: Murdoch Childrens Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/tumour-associated-macrophages-gastric-cancer/100370
• 关键词: Tumour; associated; macrophages; IL; family

Stomach cancer has a high mortality rate and a poor prognosis. Stomach cancer is one of the few cancers in which the causative pathogen had been demonstrated and eradication of Helicobacter pylori will eliminate the risk of developing cancer but the point at which tumour initiation is irreversible is unknown. Eradication of H. pylori is not always simple or effective. So investigation into initiation events in stomach cancer and development of more sophisticated treatments is warranted.

胃癌死亡率高，预后差。胃癌是少数几种已证实有致病病原体的癌症之一，根除幽门螺杆菌将消除发展为癌症的风险，但肿瘤发生的不可逆点尚不清楚。根除幽门螺杆菌并不总是简单或有效的。因此，研究胃癌的起始事件和开发更复杂的治疗方法是有必要的。