Clinical and Research Training Program for Academic Vascular Medicine Specialists

学术血管医学专家临床和研究培训计划

• 批准号: 7918051
• 负责人: MARK A CREAGER
• 金额: $ 86.29万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7918051
• 关键词: Angiography; Area; Bioethics; Blood Vessels; Cerebrovascular Disorders; Cessation of life; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Clinical Trials Design; Consultations; Educational Curriculum; Educational process of instructing; Epidemiology; Faculty; Future; Future Generations; Genetic; Goals; Grant; Hospitals; Inpatients; Intervention; Journals; Kidney; Laboratories; Leadership; Lymphedema; Magnetic Resonance Angiography; Manuscripts; Master' s Degree; Medical; Medicine; Mentors; Mesenteric artery ischemia; Methods; Operative Surgical Procedures; Oral; Outpatients; Peripheral; Peripheral arterial disease; Pharmacology; Physicians; Preparation; Public Health; Public Health Schools; Research; Research Activity; Research Project Grants; Research Training; Resources; Science; Societies; Specialist; Surgeon; Techniques; Thromboembolism; Time; Training; Training Programs; Vascular Diseases; Vasculitis; Vasospasm; Venous; Venous Insufficiency; Woman; Work; Writing; career; career development; disability; experience; medical schools; multidisciplinary; programs; protocol development; radiologist; responsible research conduct; skills; statistics

DESCRIPTION (provided by applicant): Vascular diseases constitute some of the most common causes of disability and death in Western society. Yet, few physicians have chosen vascular disease as an area of clinical specialization. Academically oriented vascular medicine training programs are required to develop vascular medicine specialists with the leadership skills and academic credentials to educate future generations of vascular specialists. Accordingly, we propose to establish a comprehensive Vascular Medicine training program that includes: 1) a core clinical curriculum taught by a multidisciplinary faculty of vascular medicine physicians, vascular surgeons and vascular radiologists; 2) an extended didactic clinical research curriculum; and 3) a mentored clinical research experience. The proposed program will admit seven trainees, each for three years. The first year of the program will include clinical training and expose the trainee to all aspects of vascular medicine including peripheral arterial disease, renal and mesenteric vascular disease, cerebrovascular disease, venous thromboembolism, venous insufficiency, lymphedema, vasculitis, vasospasm, and less common vascular disorders. Clinical time will be devoted to inpatient and outpatient vascular consultations, the noninvasive vascular laboratory, computed tomographic and magnetic resonance angiography, peripheral angiography, endovascular interventions and vascular surgery. The second and third years of training will emphasize clinical research. This will include an extended didactic clinical research curriculum emphasizing epidemiology, statistics, clinical trials design, and include principles of pharmacology, genetics in clinical investigation, bioethics and responsible research conduct and additional coursework leading to a Masters degree in Medical Science or Public Health, as appropriate given training and career goals. Coursework will be supplemented by research seminars and journal clubs. Trainees will work closely with mentors who will supervise their research activity and guide the trainees' career development. The mentored clinical research experience will include a vascular research project and teach skills in protocol development, experimental technique, methods, analysis, oral presentation, manuscript writing and grant preparation. Research activities will leverage the many clinical research programs and facilities that are available at Brigham and Women's Hospital, Harvard Medical School and the Harvard School of Public Health. These resources will provide significant opportunities for the trainee to acquire clinical research skills and facilitate a successful transition towards independence as a clinical investigator. As a consequence of the intensive clinical and research training integrated in this program, we are confident that we will successfully prepare future academic leaders in the field of Vascular Medicine.

描述（由申请人提供）： 血管疾病构成了西方社会残疾和死亡的一些最常见的原因。然而，很少有医生选择血管疾病作为临床专业领域。需要以学术为导向的血管医学培训计划，以培养具有领导技能和学术资格的血管医学专家，以教育未来几代血管专家。因此，我们建议建立一个全面的血管医学培训计划，包括：1）由血管医学医生，血管外科医生和血管放射科医生的多学科教师教授的核心临床课程; 2）扩展的教学临床研究课程;和3）指导临床研究经验。拟议的方案将招收7名受训人员，每人为期3年。该计划的第一年将包括临床培训，并使受训者接触血管医学的各个方面，包括外周动脉疾病，肾脏和肠系膜血管疾病，脑血管疾病，静脉血栓栓塞，静脉功能不全，水肿，血管炎，血管痉挛和不常见的血管疾病。临床时间将用于住院和门诊血管咨询、无创血管实验室、计算机断层扫描和磁共振血管造影、外周血管造影、血管内介入和血管外科手术。第二年和第三年的培训将强调临床研究。这将包括一个扩展的教学临床研究课程，强调流行病学，统计学，临床试验设计，并包括药理学原理，临床研究中的遗传学，生物伦理学和负责任的研究行为和额外的课程，导致医学或公共卫生硕士学位，适当的培训和职业目标。课程将由研究研讨会和期刊俱乐部补充。学员将与导师密切合作，导师将监督他们的研究活动并指导学员的职业发展。指导的临床研究经验将包括血管研究项目，并教授方案制定，实验技术，方法，分析，口头陈述，手稿写作和拨款准备方面的技能。研究活动将利用布里格姆妇女医院、哈佛医学院和哈佛公共卫生学院提供的许多临床研究项目和设施。这些资源将为受训者提供重要的机会，以获得临床研究技能，并促进成功过渡到独立的临床研究者。由于在该计划中集成了密集的临床和研究培训，我们有信心，我们将成功地准备在血管医学领域的未来学术领袖。

项目成果

Hospital budget implications of substituting dabigatran for warfarin in an anticoagulation service.

在抗凝服务中用达比加群替代华法林对医院预算的影响。

• DOI: 10.1177/1076029611416642
• 发表时间: 2012
• 期刊: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
• 作者: Atay,JulieK;Fiumara,Karen;Piazza,Gregory;Fanikos,John;Goldhaber,SamuelZ
• 通讯作者: Goldhaber,SamuelZ

Effect of angiotensin receptor blockade on insulin sensitivity and endothelial function in abdominally obese hypertensive patients with impaired fasting glucose.

血管紧张素受体阻断对空腹血糖受损的腹部肥胖高血压患者胰岛素敏感性和内皮功能的影响。

• DOI: 10.1042/cs20110284
• 发表时间: 2012
• 期刊: Clinical science (London, England : 1979)
• 作者: Perlstein,ToddS;Henry,RobertR;Mather,KierenJ;Rickels,MichaelR;Abate,NicolaI;Grundy,ScottM;Mai,Yabing;Albu,JeanineB;Marks,JenniferB;Pool,JamesL;Creager,MarkA
• 通讯作者: Creager,MarkA

Body fat distribution, incident cardiovascular disease, cancer, and all-cause mortality.

• DOI: 10.1016/j.jacc.2013.06.027
• 发表时间: 2013-09-03
• 期刊: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
• 影响因子: 24
• 作者: Britton, Kathryn A.;Massaro, Joseph M.;Murabito, Joanne M.;Kreger, Bernard E.;Hoffmann, Udo;Fox, Caroline S.
• 通讯作者: Fox, Caroline S.

A pooled analysis of the durability and predictors of treatment response of cilostazol in patients with intermittent claudication.

• DOI: 10.1177/1358863x10361545
• 发表时间: 2010-06
• 期刊: Vascular medicine (London, England)
• 作者: Pande RL;Hiatt WR;Zhang P;Hittel N;Creager MA
• 通讯作者: Creager MA

Physician alerts to prevent symptomatic venous thromboembolism in hospitalized patients.

• DOI: 10.1161/circulationaha.108.841197
• 发表时间: 2009-04-28
• 期刊: Circulation
• 影响因子: 37.8
• 作者: Piazza G;Rosenbaum EJ;Pendergast W;Jacobson JO;Pendleton RC;McLaren GD;Elliott CG;Stevens SM;Patton WF;Dabbagh O;Paterno MD;Catapane E;Li Z;Goldhaber SZ
• 通讯作者: Goldhaber SZ