THE CONTRIBUTION OF INFLAMMATION AND INSULIN RESISTANCE

炎症和胰岛素抵抗的作用

• 批准号: 7719318
• 负责人: MARK A CREAGER
• 金额: $ 0.05万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7719318
• 关键词: Atherosclerosis; Blood Vessels; Cells; Computer Retrieval of Information on Scientific Projects Database; Development; Funding; Glucose; Grant; Inflammation; Institution; Insulin Resistance; Muscle; Pain in lower limb; Purpose; Research; Research Personnel; Resources; Source; Symptoms; United States National Institutes of Health; Vascular blood supply; Walking; irritation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to determine whether inflammation, an irritation of the blood vessel wall and the inability of cells to properly use glucose for energy promote the development of atherosclerosis and worsen symptoms of muscular leg pain with walking because the blood supply to these muscles is inadequate.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这项研究的目的是确定炎症，血管壁的刺激和细胞无法正确使用葡萄糖作为能量是否会促进动脉粥样硬化的发展，并使行走时的腿部肌肉疼痛症状恶化，因为这些肌肉的血液供应不足。