Neurobiology Summer Course

描述（由申请人提供）：MBL神经生物学课程的目标是为有可能成为有创造力和生产力的神经生物学家的学生提供分子和细胞神经生物学的强化课程，由该领域的顶尖科学家教授。这是一门密集而全面的、以实验室为导向的课程，在过去的37年里，每年夏天都在马萨诸塞州伍兹霍尔的海洋生物实验室开设，在过去的25年里一直得到美国国立卫生研究院的支持。课程时间为8周，从6月中旬到8月初，分为三个部分：1)电生理学，2)分子神经生物学，3)显微镜与成像。深入探讨的主题包括电压门控和配体门控离子通道的结构/功能分析，第二信使介导的细胞信号传导，突触传递，神经调节和整合，神经细胞生物学，细胞骨架和神经突生长，以及神经可塑性。此外，该课程还组织来访科学家的特别夜间讲座。学生们还就他们在本国机构正在进行的研究进行简短的研讨会。在每个部分的最后，他们展示了他们的研究项目的结果。由于该课程继续满足国家对研究生和博士后培养的需求，它为学生提供了与国际公认的神经生物学专家一起工作的机会，使用最先进的设备。本课程的目标是将学生带到分子和细胞神经生物学知识的前沿，传授对重大未解决问题的理论理解，以及对解决这些问题有用的实验工具和方法。整合三个神经生物学部分允许学生在国际知名科学家的指导下设计多学科项目。需要资金来继续这个独特的，全国突出的培训机会，这是对我们科学未来的合理投资。项目

DESCRIPTION (provided by applicant): The goal of the MBL Neurobiology Course is to provide students who are likely to become creative and productive neurobiologists with an intensive course in Molecular and Cellular Neurobiology, taught by leading scientists in the field. It is an intensive and comprehensive, laboratory-oriented course which has been offered every summer for the past 37 years at the Marine Biological Laboratory in Woods Hole, Massachusetts, with continuous NIH support for the past 25 years. The course duration is eight weeks, from mid-June to early August, and is divided into three sections: 1) Electrophysiology, 2) Molecular Neurobiology, and 3) Microscopy and Imaging. Topics explored in depth include structure/function analysis of voltage-gated and ligand-gated ion channels, second messenger-mediated cell signaling, synaptic transmission, neuro-modulation and integration, nerve cell biology, the cytoskeleton and neurite outgrowth, and neural plasticity. In addition, the course organizes special evening lectures by visiting scientists. Students also present short seminars concerning the research they are pursuing at their home institutions. At the end of each section, they present the results of their research projects. As the course continues to meet a national need for the training of graduate and postdoctoral students, it offers students the opportunity to work with internationally recognized experts in neurobiology, using state-of-the-art equipment. The goal of the course is to bring students to the forefront of knowledge in Molecular and Cellular Neurobiology, imparting a theoretical understanding of significant unsolved problems and the experimental tools and approaches that will be useful in solving them. Integrating the three-neurobiology sections allows the students to design multidisciplinary projects under the mentoring of internationally renowned scientists. Funding is requested to continue this unique, nationally prominent training opportunity, which represents a sound investment for our scientific future. Project