SNAPTIC ORGANIZATION OF THE BASOLATERAL AMYGDALA

基底外侧杏仁核的快速组织

• 批准号: 8357407
• 负责人: DONALD G RAINNIE
• 金额: $ 3.29万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357407
• 关键词: Amygdaloid structure; Calcium-Binding Proteins; Cells; Characteristics; Collaborations; Data; Funding; Goals; Grant; Interneurons; National Center for Research Resources; Physiological; Primates; Principal Investigator; Property; Publishing; Receptor Activation; Relative (related person); Research; Research Infrastructure; Resources; Source; Staging; Techniques; United States National Institutes of Health; base; cost; nonhuman primate; serotonin receptor

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The goal of this collaboration was to use electrophysiological and immunohistochemical techniques to identify characteristic physiological properties of interneurons of the basolateral amygdala based on their expression of cell-specific calcium binding proteins. In 2009 we finalized our examinations of the effects of serotonin receptor activation on the excitability of interneurons in the BLA, as well as our studies to examine the relative distribution of interneuron subtypes in the non-human primate BLA. The final stage of this project was devoted to analyzing and publishing data.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 此次合作的目标是利用电生理学和免疫组织化学技术，根据细胞特异性钙结合蛋白的表达来识别基底外侧杏仁核中间神经元的特征生理特性。 2009 年，我们完成了血清素受体激活对 BLA 中间神经元兴奋性影响的研究，以及非人类灵长类 BLA 中间神经元亚型相对分布的研究。该项目的最后阶段致力于分析和发布数据。