LSUHSC COBRE: CORE 1: IMMUNOLOGY & CELL ANALYSIS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 免疫学和细胞分析核心(ICAC)是本委员会提出的科学项目发展的核心。它将为PJI提供设备和技术支持。免疫和细胞分析核心拥有可用的细胞技术，包括从外周血和组织中分离细胞亚群，通过流式细胞仪和组织学对细胞进行表型表征，以及细胞功能表征，包括增殖、细胞周期分析、细胞因子产生和细胞毒性。此外，ICAC还提供研究细胞信号的能力，如酪氨酸激酶磷酸化、钙通量以及核转录因子的激活和转位。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Immunology and Cell Analysis Core (ICAC) is central to the development of the scientific projects proposed in this COBRE. It will provide access to equipment and technical support to the PJI. The Immunology and Cell Analysis Core has available cellular techniques including separation of cell subpopulations from peripheral blood and tissues, phenotypic characterization of the cells by flow cytometry and histology and characterization of cell functions including proliferation, cell cycle analysis, cytokine production and cytotoxicity. In addition, the ICAC provides the capacity to study cell signaling such as tyrosine kinase phosphorylation, calcium flux and activation and translocation of nuclear transcription factors.