Dev Pilot Projects, Cross BETRNet, and other Cross BETRNet Activities

翻译研究中心的总体目标--F发展研究计划 (TRCFDRP)是开发创新和多样化的方法，专注于Barrett的食道和食道 从病因学到预防筛查的整个范围的腺癌翻译研究， 诊断学和治疗学。TRCFDRP将提供1)资金支持，2)生物信息学支持3) TRC-F资源和4)对试点研究项目和调查人员的智力监督和建议。基金 用于开发试点研究项目对持续发展和加强真相与和解基金至关重要 真相与和解基金将在第二至第五年每年拨款150,000美元用于试点项目，每年用于 TRC-F内部的试点项目，以及每年10万美元的跨中心项目。中心内和十字交叉 BETRNet指导委员会将征集、审查和奖励中心试点项目 以科学价值、影响、意义、创新、跨学科为基础的评估标准 特点，翻译潜力，具有重要意义的潜力的贡献 加强和扩展BETRNet项目以及发展为独立研究的潜力 项目。此外，跨中心试点项目将考虑申请的潜在贡献，以增加 样本量，提供免费的技能、资源和/或专业知识或与其他翻译公司合作 研究中心或其他多机构合作团体。重点将放在支持新的 调查人员以及具有新方法的老牌调查人员。为有价值的建议从 个别基础或临床研究人员，TRCFDRP领导小组将确定补充 翻译调查人员担任顾问。我们将启动一种创新的方法，以吸引专业知识 来自内部和外部的TRC-F将发布在癌症中心的网站和国家 BETRNet网站，一系列研究机会，其中每个TRC-F项目将提供 可用于协作试点项目研究的研究问题、资源、专业知识等。

The overall objective of the Translational Research Center - F Developmental Research Program (TRCFDRP) is to develop innovative and diverse approaches to focus on Barrett's esophagus and esophageal adenocarcinoma translational research across the spectrum from etiology through prevention screening, diagnostics, and therapeutics. The TRCFDRP will provide 1) financial support, 2) Bioinformatic support 3) TRC-F resources and 4) intellectual oversight and advice for pilot research projects and investigators. Funds for development of pilot research projects are critical to ongoing development and enhancement of the TRC-F and the TRC-F will allocate $150,000 per year for years 2-5 for pilot projects to be used $50,000 per year for pilot projects from within the TRC-F and $100,000 per year for cross center projects. Within-center and Cross Center Pilot Projects will be solicited, reviewed and awarded by the BETRNet Steering Committee on a merit basis with evaluation criteria based on scientific merit, impact, significance, innovation, transdisciplinary characteristics, translational potential, with great significance attached to the potential for the contribution to enhance and extend BETRNet projects as well as the potential for developing into independent research projects. In addition, cross-center pilot projects will consider potential contribution of applications to increase sample size, provide complimentary skills, resources and/or expertise or collaborations with other Translational Research Centers or other multi-institutional cooperative groups. Emphasis will be placed on supporting new investigators as well as established investigators with new approaches. For meritorious proposals from individual basic or clinical investigators, the TRCFDRP leadership group will identify complementary translational investigators to serve as advisors. An innovative approach that we will initiate to engage expertise from both inside and outside the TRC-F will be to post on the Cancer Center website and the national BETRNet website, a series of Research Opportunities in which each TRC-F project will provide a list of research questions, resources, expertise, etc. that will be available for collaborative pilot project research.