Developmental Research Program

Case G1癌症孢子发育研究计划(SDRP)的总体目标是开发 创新和多样化的方法，专注于Gl癌从病因学到范围的翻译研究 通过预防筛查、诊断、治疗和生存。孢子发育研究进展 该计划将提供1)财务支持，2)核心设施服务，3)为飞行员提供智力监督和建议 研究项目和调查人员。重点将放在支持新的调查人员以及 具有治疗Gl癌症的新方法的老牌研究人员。为了刺激翻译研究，试点项目 有2名Co-Pi，1名基础研究员和1名临床研究员将优先考虑。为有价值的建议从 单独的基础或临床研究人员，SDRP领导小组将确定补充翻译 调查人员担任顾问。将制定特别计划，以刺激新领域的G1癌症研究 而不是结直肠癌。Gl孢子案认为试点项目机制是一个重要的 启动高风险/高影响研究的机会，并将相应地为以下项目提供适当的优先顺序 这样的提议。在案例医学院的支持下，案例综合癌症中心和 根据孢子基金，可持续发展计划每年最多可资助4个试验项目，每个项目的费用为50,000美元。试点项目的可得性 将通过多个机构范围的电子通知系统，通过与部门的直接通信来宣布 负责人和院长，并邀请具有令人兴奋的新方法的特定科学家。试点提案将是 SDRP评估小组使用NIH 9分评分系统进行评估，评估小组由选定的一系列 参与G1癌症研究并在NIH和其他国家拥有丰富经验的教职员工 组织同行评议研究部分。

The overall objective of the Case Gl Cancer SPORE Developmental Research Program (SDRP) is to develop innovative and diverse approaches to focus on Gl Cancer translational research across the spectrum from etiology through prevention screening, diagnostics, therapeutics, and survivorship. The SPORE Developmental Research Program will provide 1) financial support, 2) Core Facility Services and 3) intellectual oversight and advice for pilot research projects and investigators. Emphasis will be placed on supporting new investigators as well as established investigators with new approaches to Gl cancers. To stimulate translational research, pilot projects with 2 Co-PI's, one basic and one clinical investigator, will be given preference. For meritorious proposals from individual basic or clinical investigators, the SDRP leadership group will identify complementary translational investigators to serve as advisors. Special plans will be instituted to stimulate Gl cancer research in new areas other than colorectal cancer. The Case Gl SPORE considers the pilot project mechanism to be an important opportunity for initiation of high risk/high impact research and will accordingly provide appropriate prioritization for such proposals. With support from the Case School of Medicine, The Case Comprehensive Cancer Center and SPORE Funds, the SDRP will support up to 4 pilot projects per year at $50,000 each. Availability of pilot projects will be announced by multiple, institution wide, electronic notice systems, by direct communication with department heads and deans and by invitations to specific scientists with exciting new approaches. Pilot proposals will be evaluated using the NIH 9 point scoring system by the SDRP Evaluation Panel composed of selected series of faculty members with involvement in Gl Cancer Research and extensive experience in NIH and other national organization peer review study sections.