Developmental Research Projects

发展研究项目

• 批准号: 10005931
• 负责人: Nathan A. Berger
• 金额: $ 6.68万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-18 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10005931
• 关键词: Affect; Award; Biological; Biomedical Engineering; Breast; Cancer Center; Clinical; Collaborations; Colorectal; Communication; Communities; Comprehensive Cancer Center; Core Facility; Data; Development; Diagnosis; Discipline; Early Diagnosis; Epidemiology; Ethnic group; Etiology; Evaluation; Faculty; Financial Support; Funding; Future; Genetic; Goals; Grant; Head; Hospitals; Individual; Informatics; Institution; Leadership; Lung; Malignant Neoplasms; Malignant neoplasm of gastrointestinal tract; Molecular; Monitor; Outcome; Peer Review Organizations; Performance; Pilot Projects; Population; Prevention; Productivity; Program Evaluation; Program Research Project Grants; Prostate; Reporting; Reproduction spores; Research; Research Activity; Research Methodology; Research Personnel; Research Project Grants; Scientist; Series; Services; Sociology; Study Section; System; Translational Research; United States National Institutes of Health; University Hospitals; anticancer research; base; burden of illness; cancer health disparity; cancer research center director; community based participatory research; comparative effectiveness; experience; high risk; innovation; interest; meetings; member; mortality; novel; novel strategies; preference; programs; psychosocial; racial and ethnic; social; socioeconomic disadvantage; socioeconomics; translational scientist

CASE COMPREHENSIVE CANCER CENTER DISPARITIES SPORE DEVELOPMENTAL RESEARCH PROGRAM (DRP) SUMMARY/ABSTRACT The overall objective of the Case Comprehensive Cancer Center Disparity SPORE Developmental Research Program (DRP) is to develop innovative and diverse approaches to focus on disparities translational research across the spectrum from etiology, prevention, early detection, diagnosis, therapy, survival, disease burden, and mortality in cancers found to disparately affect disadvantaged socioeconomic and racial/ethnic groups. The Case Disparities SPORE DRP will provide 1) Financial support, 2) Core Facility Services, and 3) Intellectual Oversight and Advice for pilot research projects and investigators. Emphasis will be placed on supporting new investigators, as well as, established investigators with new approaches to Disparities Research. To stimulate translational research, pilot projects with 2 Co-PI's, one basic, one clinical and/or one community-based investigator, will be given preference. For meritorious proposals from individual basic, clinical or community- based investigators, the DRP leadership group will identify complementary translational investigators to serve as advisors. The Case Disparities SPORE considers the pilot project mechanism to be an important opportunity for initiation of high risk/high impact research and will accordingly provide appropriate prioritization for such proposals. With support from the collaborating institutions and $50,000 from the SPORE Grant Award, the Case Disparities SPORE will support four pilot projects per year at $50,000 each. Solicitation for pilot projects will be announced by multiple, institution wide, electronic notice systems, by direct communication with Case Comprehensive Cancer Center directors, department heads and deans of participating institutions and by invitations to specific scientists with exciting new approaches. Pilot proposals will be evaluated using the NIH 9 point scoring system by the DRP Evaluation Panel composed of selected series of faculty members representing all participating institutions, with expertise in basic, clinical, translational, epidemiological, sociological and community-based research, and with involvement and experience in NIH and other national organization peer review study sections. Ongoing intellectual and performance oversight, evaluation and advice regarding implementation, conduct and productivity of research will be monitored and guided by a regular series of reports, scientific presentations and meetings between investigators and leadership.

病例综合癌症中心差异孢子 医疗研究中心（DRP） 总结/摘要 病例综合癌症中心差异孢子发育研究的总体目标 计划（DRP）是开发创新和多样化的方法，专注于差异翻译研究 从病因学、预防、早期发现、诊断、治疗、生存、疾病负担和 癌症死亡率严重影响弱势社会经济和种族/族裔群体。的 案例差异SPORE DRP将提供1）财务支持，2）核心设施服务，3）知识 对试点研究项目和调查人员的监督和咨询。重点将放在支持新的 研究人员，以及，建立了研究人员与新的方法，以差异研究。刺激 转化研究，与2个Co-PI的试点项目，一个基础，一个临床和/或一个基于社区的 调查员将优先考虑。对于个人基础，临床或社区的优秀建议- 基于调查员，DRP领导小组将确定补充翻译调查员， 作为顾问案例差异SPORE认为试点项目机制是一个重要的机会 启动高风险/高影响研究，并将相应地为此类研究提供适当的优先级 提案在合作机构的支持下，并从SPORE资助奖中获得50，000美元， Disparities SPORE将每年支持四个试点项目，每个项目5万美元。试点项目的征集工作将 通过与Case直接沟通，由多个机构范围内的电子通知系统宣布 综合癌症中心主任、参与机构的部门负责人和院长， 邀请特定的科学家用令人兴奋的新方法。试点提案将使用NIH 9 点评分系统由DRP评估小组组成的一系列选定的教员代表 所有参与机构，具有基础、临床、转化、流行病学、社会学和 以社区为基础的研究，并参与和经验，在美国国立卫生研究院和其他国家组织同行 审查研究章节。持续的知识和业绩监督、评价和咨询， 研究的执行、进行和成果将受到一系列定期报告的监测和指导， 研究人员和领导层之间的科学演示和会议。