Biostatistic Core

生物统计核心

• 批准号: 8246725
• 负责人: Soledad A Fernandez
• 金额: $ 14.11万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-15 至 2017-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8246725
• 关键词: Address; Adopted; Biological; Biometry; Biostatistics Core; Clinical; Collaborations; Complex; Data; Data Analyses; Data Display; Data Quality; Decision Making; Drug Formulations; Ensure; Experimental Designs; Inferior; Investigation; Lead; Literature; Maintenance; Mammary Neoplasms; Measurement; Methodology; Methods; Modeling; Outcome Measure; Play; Population Study; Procedures; Reporting; Research; Research Personnel; Resources; Role; Sample Size; Sampling; Security; Services; Staging; Statistical Methods; Statistical Models; Statistical Study; Statistical sensitivity; Testing; Thinking; Validation; Visual; Work; Writing; base; data integration; data integrity; data management; design; expectation; experience; genetic analysis; meetings; primary outcome; repository; research study; success

The principal objective of the Biostatistics Core will be to provide project investigators a centralized resource for biostatistics expertise. Statistical issues will be addressed at all levels of investigation: from the design of experiments, to the maintenance of data quality; and from conclusions based on formal hypothesis testing, to important leads discovered by thorough data exploration. In support of this objective, the specific aims of the Core include: 1. Collaborate with project investigators in the formulation of unambiguous hypotheses and hypothesis testing strategies, and in the design of experiments and population studies. 2. Provide support for all projects with: formal hypothesis tests in experimental data that ensure strong conclusions; exploratory analyses that lead to further experiments, refined hypotheses, or discoveries; frequent collaborative meetings about refining design, sample size, and resource use as evidence is accumulated; statistical modeling and sensitivity analyses of complex data; and visual displays of data that clarify conclusions and uncover leads. 3. Provide data transfer, management, and integration services that ensure high integrity, security and investigator accessibility. 4. Investigate new methodologies to directly address difficult data or design problems.

生物统计学核心的主要目标是为项目调查人员提供集中资源 用于生物统计学专业知识。统计问题将在各个级别的调查中解决： 实验，以维持数据质量；从基于正式假设检验的结论到 通过彻底的数据探索发现的重要潜在客户。为了支持这个目标， 核心包括： 1。与项目调查人员合作制定明确的假设和假设 测试策略，以及实验和人口研究的设计。 2.在实验数据中为所有项目提供支持：正式假设测试，以确保强大 结论；探索性分析导致进一步的实验，精致的假设或发现； 关于精炼设计，样本量和资源使用作为证据的频繁协作会议是 积累;复杂数据的统计建模和灵敏度分析；和数据的视觉显示 这阐明了结论和发现的铅。 3。提供数据传输，管理和集成服务，以确保高完整性，安全性和 调查员可访问性。 4.研究新方法，以直接解决困难的数据或设计问题。