Variation in Cigarettes, Tobacco use Behaviors and Exposures in ITC Countries

项目3扩展了项目1概述的国贸中心调查方法，在国贸中心六个国家收集补充数据，其中两个是发达国家（即，美国和英国）和四个中低收入国家（即，中国、马来西亚、墨西哥、泰国），目的是检查主要品牌品种之间卷烟特征的差异，并探索这些差异与烟草控制政策、烟草使用行为和暴露于烟草的关系。 不同国家的烟草烟雾成分。项目3有三个具体目标。目标1涉及跟踪烟草市场，建立一个主要卷烟品牌的信息库，并对零售商一级的产品营销和定价活动进行评估。目标2有两个与香烟的结构和成分有关的组成部分：（a）鉴定为储存库获得的香烟， 从个体中获得能够影响烟雾化学和消费者可接受性的关键设计和物理特征;以及（B）开发能够用于可靠地区分合法品牌和假冒品牌的香烟品牌的物理特征组。目标3旨在研究吸烟行为和暴露的个人差异，也包括两个组成部分：（a）在项目1的ITC队列参与者的子样本中研究烟草使用行为的差异在多大程度上可以解释为 尼古丁摄入量和尼古丁代谢的测量;以及（B）比较烟草使用行为、尼古丁摄入量和尼古丁代谢如何与高资源和低收入国家内部和之间的社会剥夺/社会经济地位指标相关。

Project 3 extends the ITC survey methodology outlined in Project 1, by undertaking supplementary data collection in six ITC countries, two developed (i.e., US & UK) and four LMICs (i.e., China, Malaysia, Mexico, Thailand) with the goal of examining variation in cigarette characteristics among leading brand varieties, and exploring how these differences relate to tobacco control policies, tobacco uses behaviors, and exposure to selected tobacco smoke constituents in different countries. Project 3 has three specific aims. Aim 1 involves tracking the tobacco market and establishing a repository of leading cigarette brands, linkable to retailer-level evaluations of product marketing and pricing activities. Aim 2 has two components related to the construction and composition of cigarettes: (a) characterizing cigarettes obtained for the repository as well as from individuals for key design and physical features that can influence smoke chemistries and consumer acceptability; and (b) developing a panel of physical features of cigarettes brands that can be used to reliably distinguish legitimate from counterfeit brands. Aim 3, which seeks to examine person-level variation in smoking behaviors and exposures, also involves two components: (a) examining in a subsample of the ITC cohort participants in Project 1 the extent to which variation in tobacco use behaviors can be explained by measures of nicotine intake and nicotine metabolism; and (b) comparing how tobacco use behaviors, nicotine intake and nicotine metabolism are related to indicators of social deprivation/socioeconomic status, both within and between high resource and LMICs.