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This application aims to set the foundation for a longitudinal population-based study of relevant health issues in older Chinese persons by leveraging a comprehensive model of community engagement. The diverse US population is rapidly aging; as such, it is imperative from a public health perspective that we have accurate understanding of relevant health issues among specific racial/ethnic populations. There are an estimated 3.8 million Chinese in the US, and Chicago has one of the largest aggregations. Despite the rapid growth, we have the most rudimentary understanding of many critical health issues facing the older Chinese population (cognitive impairment, physical disability, racial discrimination, psychological distress, social isolation, filial piety, cultural values, and elder mistreatment [elder abuse, neglect and exploitation perpetrated by others as well as elder self-neglect]. Furthermore, there has been inadequate community network and support necessary to empower the Chinese community to be fully engaged in health sciences research. These impediments necessitate the further development and implementation of sustainable and equal partnership of both community and researchers through reciprocal transfer of expertise to improve the health of the Chinese population. Several challenges to conducting a community-engaged population study in a Chicago Chinese population make the proposed developmental work an important first step to conducting a longitudinal population-based cohort study. These challenges are: 1) US Chinese older persons have been reluctant to participate in government sponsored research and sustainable community support has been inadequate; 2) there is incomplete enumeration at the local level of Chinese older persons in the community; and 3) there are marked linguistic and cultural barriers that make a population-based study challenging. In this proposed work, a bilingual and bicultural principal investigator and an experienced interdisciplinary investigative team at the Rush Institute for Healthy Aging are collaborating with Chinese community to overcome these barriers. The specific aims of this feasibility study are to: 1) Further engage the community to build a culturally appropriate and sustainable collaborative partnership in support of the study; 2) Pilot a random block census of older Chinatown residents; and 3) Examine the linguistic and cultural barriers of studying relevant health disparity issues. The findings from this proposal and community engagement activities can be critical to the successful conduct of a community-engaged longitudinal population-based study of relevant health issues in Chinese older persons.
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国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: