INTERACTION OF EMOTIONAL PERCEPTION AND VISUAL ATTENTION

情感感知和视觉注意力的相互作用

• 批准号: 8117710
• 负责人: LUIZ PESSOA
• 金额: $ 37.62万
• 依托单位: UNIV OF MARYLAND, COLLEGE PARK
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-06-01 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8117710
• 关键词: Affect; Affective; Alzheimer' s Disease; Amygdaloid structure; Anterior; Anxiety Disorders; Attention; Autistic Disorder; Awareness; Behavior; Behavioral; Behavioral inhibition; Brain; Charge; Cognition; Cognitive; Complex; Conflict (Psychology); Databases; Emotional; Emotions; Epilepsy; Event; Functional Magnetic Resonance Imaging; Generations; Goals; Human; Incentives; Insula of Reil; Knowledge; Lateral; Light; Literature; Major Depressive Disorder; Medial; Mental disorders; Modeling; Motivation; Parietal Lobe; Perception; Performance; Prefrontal Cortex; Process; Punishment; Recording of previous events; Recruitment Activity; Relative (related person); Research; Resource Allocation; Resources; Rewards; Role; Schizophrenia; Series; Stimulus; Structure; System; Testing; Visual Cortex; Visual Perception; Visual attention; Work; affective neuroscience; aversive conditioning; base; emotional stimulus; executive function; flexibility; improved; information processing; innovation; knowledge base; nervous system disorder; public health relevance; response

DESCRIPTION (provided by applicant): Our long-range goal is to contribute to a better understanding of the basic mechanisms by which emotional/motivational and cognitive brain systems interact in the generation of complex behavior. The objective of the present application is to understand the mechanisms of interaction between these systems during tasks that recruit "top-down control", including inhibitory control and conflict processing. The project's central hypothesis is that affective significance confers a competitive advantage toward the processing of emotion-laden information (relative to neutral items) and that emotional stimuli are prioritized as a function of the stimuli's affective history and affective context. We will test our hypotheses by pursuing three specific aims, which will employ a combination of behavioral and functional magnetic resonance imaging (fMRI) studies: Aim #1: Determine how inhibition interacts with emotion; Aim #2: Determine how conflict processing interacts with emotion; Aim #3: Determine how executive function interacts with motivation. Affective significance will be manipulated in a number of ways, including aversive conditioning and reward/punishment (via monetary incentives). Throughout these aims, we will attempt to identify the brain networks underlying interactions between emotion and cognition. We anticipate that an item's affective history and context will bias processing in favor of emotion-laden information, and that such bias will be manifested in multiple ways across behavior, and, correspondingly, across multiple levels of the brain. Importantly, by providing a better understanding of cognitive-emotional interactions during normal behavior, our research can help understand the mechanisms that potentially go awry in many debilitating mental illnesses. PUBLIC HEALTH RELEVANCE: The proposed research will advance the knowledge database concerning the basic mechanisms of how cognition and emotion/motivation interact in the domains of inhibitory control and conflict processing in humans. Such knowledge is of importance because many neurological disorders and mental illnesses are characterized by profound deficits in cognitive and emotional interactions, including epilepsy, Alzheimer's disease, autism, major depression, anxiety disorders, and schizophrenia.

描述(由申请者提供)：我们的长期目标是更好地理解情绪/动机和认知大脑系统在复杂行为产生过程中相互作用的基本机制。本申请的目的是了解在包括抑制控制和冲突处理在内的“自上而下控制”的任务期间，这些系统之间的相互作用机制。该项目的中心假设是，情感重要性在处理充满情感的信息(相对于中性项目)方面具有竞争优势，情感刺激的优先顺序取决于刺激的情感历史和情感背景。我们将通过追求三个具体目标来验证我们的假设，这三个目标将使用行为和功能磁共振成像(FMRI)研究的组合：目标1：确定抑制如何与情绪相互作用；目标2：确定冲突处理如何与情绪相互作用；目标3：确定执行功能如何与动机相互作用。情感意义将以多种方式被操纵，包括厌恶的条件反射和奖惩(通过金钱激励)。通过这些目标，我们将试图确定情绪和认知之间相互作用的大脑网络。我们预计，一项物品的情感历史和背景会使加工偏向于情感丰富的信息，这种偏见将在行为上以多种方式表现出来，相应地，也会表现在大脑的多个层面。重要的是，通过更好地理解正常行为中的认知-情绪相互作用，我们的研究可以帮助理解许多令人衰弱的精神疾病中潜在出错的机制。 公共卫生相关性：拟议的研究将推进关于人类认知和情绪/动机在抑制控制和冲突处理领域如何相互作用的基本机制的知识库。这些知识很重要，因为许多神经疾病和精神疾病的特点是认知和情感互动的严重缺陷，包括癫痫、阿尔茨海默病、自闭症、严重抑郁症、焦虑症和精神分裂症。