Research Core

少数民族青年和成年人健康与风险中心（CHARM）致力于少数民族社区的慢性病预防，重点是青年和年轻人。CHARM汇集了来自加州大学，旧金山弗朗西斯科（UCSF），SF总医院（SFGH -一个首屈一指的安全网机构提供医疗保健的SF的多样化人口），SF州立大学（少数民族服务机构与大型拉丁裔学生团体）的研究人员。北方加州凯撒永久研究部、加州大学伯克利分校和斯坦福大学以及社区合作伙伴。该方法是明确的跨学科，将具有医学，儿科学，家庭医学和妇产科临床专业知识的研究人员与具有差异研究，遗传学，流行病学，生物统计学，定性方法，公共卫生，传播科学和健康心理学方法学专业知识的研究人员联系起来。 CHARM的3个研究子项目的共同纲领性目标是了解在青年和青年期采取的行为以及在这个年龄段存在的其他风险因素对种族/少数民族人群慢性病的影响。了解生物，行为，社会，文化和环境因素在慢性病风险中的作用，并对这些潜在的作用采取行动。 这些机制最有希望改善少数群体的健康状况，并最终消除健康差距。研究核心的主要作用是协调和支持所有3个拟议的子项目，以实现这一总体目标。此外，研究核心与培训和参与社区健康外展（ECHO）核心沟通，以实现CHARM的总体目标。3个子项目的目标 CHARM的总体目标将由该核心中的领导、专业知识、通信功能、方法支持和建模有效地服务。 研究核心有以下主要目的和目标： 研究核心目标1.协调3个子项目的方法支持，以优化设计、数据系统和分析方法。 研究核心目标2.将来自新开发的OurSpace邻里数据库的空间数据与来自CHARM研究子项目的个人数据联合收割机相结合： (a)绘制弗朗西斯科的差异图，以及导致这些差异的行为和资源分布/可用性，供CHARM培训和ECHO核心使用，以及（B）为3个研究子项目中的2个提供区域级数据进行分析。 研究核心目标3.综合CHARM的3个子项目的结果，以开发模型，告知青少年和青年时期可能发生的影响事件对以后生活的差异。这些模式将有助于传播次级项目的成果，特别是通过欧共体人道处核心项目，并将包括： (a)一个复杂的系统模型，说明青少年和青年期差异的决定因素之间的关系， (b)现有模型的扩展，用于理解加州差异决定因素干预的政策含义。 研究核心将由罗伯特·A·希亚特医学博士，哲学博士。他是UCSF流行病学与生物统计学教授兼主席，在领导力，流行病学，监测和差异研究方面具有专业知识。 其他关键人员包括大卫·拉科普夫博士。ScD。每小时在先进的流行病学方法和统计建模方面的专业知识，以及比宾斯-多明戈博士。PhD，MD，MAS，CHARM的总PI，在临床医学，流行病学和慢性病干预建模方面具有专业知识。

he Center for Health And Risk in Minority youth and adults (CHARM) is dedicated to chronic disease prevention in minority communities, with a focus on youth and young adults. CHARM brings together investigators from the University of California, San Francisco (UCSF), SF General Hospital (SFGH - a premier safety net institution providing healthcare to the diverse population of SF), SF State University (a minority serving institution with a large Latino student body). Northern California Kaiser Permanente Division of Research, UC Berkeley, and Stanford University, as well as community partners. The approach is explicitly transdisciplinary, linking investigators with clinical expertise in medicine, pediatrics, family medicine, and obstetrics and gynecology with those with methodological expertise in disparities research, genetics, epidemiology, biostatistics, qualitative methods, public health, communication sciences, and health psychology. The 3 CHARM research sub-projects share the programmatic goal of understanding the influence that behaviors adopted in youth and young adulthood and other risk factors presence during this age period exert as precursors to chronic disease in racial/ethnic minority populations. Understanding the role of biological, behavioral, social, cultural, and environmental factors in chronic disease risk and acting on these underlying mechanisms holds the best hope for improving minority health and ultimately eliminating health disparities. The primary role of the Research Core is to coordinate and support all 3 proposed sub-projects in achieving this overall goal. Additionally, the Research Core communicates with the Training and Engaging Community forHealth Outreach (ECHO) cores to achieve the overall goals of CHARM. The Aims of each of the 3 sub-projects and the overall goal of CHARM will be efficiently and effectively served by the leadership, expertise, communication functions, methods support, and modeling that will reside in this Core. The Research Core has the following primary aims and objectives: Research Core Aim 1. To coordinate methodological support utWlzed in each of the 3 sub-projects to optimize design, data systems, and analytic methods. Research Core Aim 2. To combine spatial data from a newly developed OurSpace Neighborhood Database with individual-level data from CHARM research sub-projects: (a) to map disparities in San Francisco, as well as behaviors and distribution/availability of resources that contribute to these disparities for use by the CHARM Training and ECHO cores, and (b) to provide area-level data for analyses within 2 of the 3 research sub-projects. Research Core Aim 3. To synthesize results of the 3 CHARM sub-projects in order to develop models that will inform the likely impact events in adolescence and young adulthood have on disparities in later life. These models will aid in the dissemination of the results of the sub-projects, particularly by the ECHO Core, and will include: (a) a complex systems model to illustrate the relationships of the determinants of disparities in adolescence and young adulthood, and (b) an extension of an existing model for understanding the policy implications oi interventions on determinants of disparities in California. The Research Core will be directed by Robert A. Hiatt. MD, PhD. Who is Professor and Chair of Epidemiology & Biostatistics at UCSF with expertise in leadership, epidemiology, surveillance, and disparities research. Other key personnel include Dr. David Rehkopf. ScD. MPH. with expertise in advanced epidemiologic methods and statistical modeling, and Dr. Bibbins-Domingo. PhD, MD, MAS who is overall PI of CHARM and who has expertise in clinical medicine, epidemiology, and chronic disease intervention modeling.