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Mouse coronary micro computed tomography

Mouse coronary micro computed tomography
小鼠冠状动脉显微计算机断层扫描
批准号：
8344932
负责人：
HAN WEN
金额：
$29.38万
依托单位：
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8344932
关键词：
ApoE knockout mouseCoronaryCoronary ArteriosclerosisCoronary arteryDataDevelopmentGoalsHeartImageLaboratoriesManuscriptsMusPhaseProtocols documentationSourceStructureSynchrotronsVariantX-Ray Computed Tomographymouse model

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中文摘要
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英文摘要
Prior to our study, microCT of coronary artery casts have shown anatomical variations in genetically modified mouse models, but has not been developed to image the coronary wall structures in mouse models of coronary artery disease. We have developed the imaging protocol and obtained data in apoE knockout mice that demonstrate coronary wall and plaque imaging in intact hearts. The manuscript is being prepared for submission, and more data acquired at the Argonne National Laboratory synchrotron x-ray source are being analyzed.
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