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Advanced x-ray imaging and computed tomography

Advanced x-ray imaging and computed tomography
先进的 X 射线成像和计算机断层扫描
批准号：
8557937
负责人：
HAN WEN
金额：
$85.29万
依托单位：
NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8557937
关键词：
AbdomenBiologicalDevelopmentDiffusion Magnetic Resonance ImagingDoseGoalsImageMethodsMicroscopicMicroscopyMolecular ProbesMotionPathologyPhasePhysiologicalRadiationSamplingSpeedStructureTechniquesTechnologyX-Ray Computed Tomographybioimagingclinical applicationcopingdensityinterestresearch study

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中文摘要
翻译
为了寻求高灵敏度的X射线位相衬度成像，我们制作了世界上第一个200 nm周期的硬X射线光栅，并利用这种高密度光栅进行了第一次位相衬度成像实验。我们还提出了一种特别适合于生物样品的X射线显微技术，并为这项技术确定了分子探针。我们发明了一种加速X射线相衬成像的方法，这对这项技术的临床应用是一个巨大的挑战。
英文摘要
On the quest for high sensitivity x-ray phase-contrast imaging, we fabricated the first 200 nm period hard x-ray gratings and performed the first phase-contrast imaging experiments with such high density gratings in the world. We also proposed a new way of doing x-ray microscopy which is particularly suitable for biological samples and identified molecular probes for this technology. We invented a method to speed up x-ray phase-contrast imaging which is a significant challenge for clinical applications of this technology.
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会议论文
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