LONGITUDINAL T1? MRI OF ADULTS WITH CHONDROMALACIA FOLLOWING ARTHROSCOPY

纵向T1？

• 批准号: 8361975
• 负责人: Nicola FENTY
• 金额: $ 3.08万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361975
• 关键词: Adult; Arthroscopy; Cartilage; Funding; Grant; Health; Lesion; Magnetic Resonance; Magnetic Resonance Imaging; National Center for Research Resources; Operative Surgical Procedures; Play; Principal Investigator; Procedures; Relaxation; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; cartilage repair; cost; optical imaging

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. It is has been previously demonstrated that an elevated T1¿ relaxation rate correlates with focal cartilage lesions from arthroscopically confirmed chondromalacia. It has yet to be shown what effects, if any, procedures that occur during this arthroscopy, deburring and chondroplasty, play in either subsequent cartilage repair or degeneration. To determine the post-surgical effects of these procedures, longitudinal T1¿ MRI was performed to track any subsequent changes of cartilage integrity and health. This study tracks the progression of cartilage health following these arthroscopic procedures using T1¿ MRI at 3 and 9 months post-surgery.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 之前已经证明，T1 ²弛豫率升高与局灶性相关 关节镜检查证实的软骨软化症造成的软骨损伤。 它还没有被证明是什么 影响，如果有的话，发生在这个关节镜手术，去毛刺和软骨成形术，发挥 在随后的软骨修复或退化中。 为了确定术后影响， 在这些程序中，进行纵向T1 <$MRI以跟踪软骨的任何后续变化， 正直和健康。 这项研究跟踪软骨健康的进展， 在术后3个月和9个月使用T1 <$MRI进行关节镜手术。