DIRECT ELECTRON DETECTOR

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 直接电子探测（DDD）传感器直接对高能电子进行成像。通过避免闪烁体的电子-光转换过程，DDD实现了前所未有的灵敏度和分辨率。DE-12相机系统由Direct Electron在圣地亚哥开发，基于12 Mpixel DDD传感器，具有6微米像素的3 K x 4K阵列。它为初级电子提供了非常高的信噪比（SNR）（>30：1），可以进行单电子计数。它还具有每1200万像素帧25毫秒的快速读出速率。它可以放置在我们任何JEOL电子显微镜（JEM 3200 FSC和JEM 2200 FSC）的相机室中。我们使用该公司的演示装置进行分辨率测试。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Direct electron detection (DDD) sensor images high-energy electrons directly. By avoiding the electron-to-light conversion process of a scintillator, the DDD achieves unprecedented sensitivity and resolution. The DE-12 Camera System developed by Direct Electron in San Diego is based on a 12 Mpixel DDD sensor featuring a 3K by 4K array of 6 micron pixels. It offers very high signal-to-noise ratio (SNR) for primary electrons (>30:1) enables single electron counting.It also has a fast readout rate with 25 msec per 12 Megapixel frame. It can be placed in the camera chamber in any of our JEOL electron microscopes (JEM3200FSC and JEM2200FSC). We perform a resolution test with a demo unit from the company.