The Stanford-SLAC CryoEM Center (S2C2)

斯坦福-SLAC 冷冻电镜中心 (S2C2)

• 批准号: 10428976
• 负责人: Wah Chiu
• 金额: $ 30.94万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10428976
• 关键词: Administrator; Adopted; Advisory Committees; Archives; Collaborations; Communities; Computer software; Computers; Cryo-electron tomography; Cryoelectron Microscopy; Data; Data Collection; Department of Energy; Deposition; Development; Educational Curriculum; Educational workshop; Electron Microscope; Electron Microscopy; Electronic Mail; Electrons; Equipment; Evaluation; Funding; Geography; Home; Human Resources; Image; Infrastructure; Institution; International; Laboratories; Learning; Light; Maps; Methods; Mission; Modeling; Online Systems; Persons; Physics; Preparation; Process; Professional Organizations; Protocols documentation; Request for Applications; Research; Research Personnel; Research Project Grants; Resolution; Resources; Roentgen Rays; Running; Sampling; Scientist; Services; Ships; Source; Specialist; Specimen; Structural Biologist; Structural Models; Structure; Synchrotrons; Techniques; Technology; Three-Dimensional Image; Time; Training; Training Programs; Universities; computer cluster; computer infrastructure; contrast imaging; data acquisition; data exchange; data quality; data repository; data streams; detector; electron diffraction; follow-up; free-electron laser; image processing; innovation; instrument; meetings; member; operation; peer; preservation; programs; prospective; protein data bank; recruit; residence; response; screening services; structural biology; theories

Project Summary This is a supplement request for providing a cryo-specimen screening service to the community. We will use our existing equipment in the Center to provide this activity. We anticipate that the Talos Arctica (200 kV) and the Tundra (100 kV) electron microscopes will be used for the proposed activity. We will recruit a full-time staff member for this activity and will advertise our service through 3DEM and our user email lists. We anticipate that this service will expand the dissemination of cryoEM technology to investigators who do not have expertise or facilities in their institutions. All the users need to apply this service via our existing project application process and evaluated by our user project evaluation committee prior to allocating staff and instrument time for the approved projects.

项目摘要 这是为社区提供低温筛查服务的补充要求。我们将 使用我们现有的设备在中心提供此活动。我们预计塔洛斯山脉 （200 kV）和苔原（100 kV）电子显微镜将用于提出的活动。我们将 招募全职工作人员参加此活动，并将通过3DEM和我们的服务宣传我们的服务 用户电子邮件列表。我们预计这项服务将将冷冻技术的传播扩展到 在其机构中没有专业知识或设施的调查人员。所有用户需要应用此信息 通过我们现有的项目申请流程提供服务，并通过我们的用户项目评估进行评估 委员会在为批准的项目分配工作人员和仪器时间之前。