FURTHER PROVING OF X-RAY FIBRE DIFRACTION DIAGNOSTIC TEST FOR PROSTATE CANCER

进一步证明 X 射线光纤衍射诊断测试对前列腺癌的影响

• 批准号: 8361290
• 负责人: VERONICA JAMES
• 金额: $ 1.77万
• 依托单位: ILLINOIS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361290
• 关键词: Address; Biophysics; Diagnostic tests; Fiber; Funding; Grant; Growth; Malignant Neoplasms; Malignant neoplasm of prostate; National Center for Research Resources; Operative Surgical Procedures; Patients; Pattern; Principal Investigator; Research; Research Infrastructure; Resources; Roentgen Rays; Sampling; Skin; Source; Testing; Tissues; United States National Institutes of Health; cost; men

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. Although fiber diffraction results to date reveal 100% correlation between the presence of prostate cancer in the patient and a particular change in the resultant pattern for skin samples, this proposal aims to address the following unresolved questions: 1. How early in the cancer growth is the change in the diffraction pattern observed? 2. Is skin the best tissue to use? 3. Do changes disappear following successful surgery or other treatments? 4. Is there a clear difference, observed for all patients, between the fibre diffraction patterns from patients with high and low grade prostate cancer? A positive answer to any or all of these would greatly enhance the usefulness of this test for all men.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 尽管迄今为止的纤维衍射结果显示， 针对患者的前列腺癌以及皮肤样本的所得图案的特定变化，该提议旨在解决以下未解决的问题： 1.在癌症生长的多早观察到衍射图案的变化？ 2.皮肤是最好的组织吗？ 3.在成功的手术或其他治疗后，变化是否会消失？ 4.在所有患者中观察到的纤维衍射 高级别和低级别前列腺癌患者的模式？ 对任何或所有这些问题的肯定回答将大大提高该测试的实用性， 都是男人