HIGH LIGHT OUTPUT SCINTILLATORS FOR X-RAY DIFFRACTION APPLICATIONS

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 这项工作的目标是开发更明亮、更高分辨率的闪烁体，以提高为结构生物学应用设计的探测器的性能，并降低成本。这项研究由美国国立卫生研究院和能源部提供的各种SBIR赠款资助，但在18ID的真实束流条件下对它们进行测试是BioCAT P41赠款核心项目I的一部分。目前，我们正在研究由CsI：Tl，Sm，结构的ZnTe：OM和结构的ZnSe：Te制成的薄膜，作为高亮度、高空间分辨率和快速衰减时间的闪烁体的可能候选者。到目前为止，最有希望的是ZnSe：TE，其亮度是通常用于这些应用的商用MinR-2000屏幕的180%。已经用EMCCD和增强型CCD摄像机对它们进行了18ID测试，以评估它们是否适合建造时间分辨散射探测器。这些实验的结果已经提交到NIMA上发表。我们将很快收到一台能够达到3600帧/秒的增强型CMOS相机，当我们找到合适的闪烁体时，我们最终将开发成一个探测器系统(70x70 mm活动区域，~67微米像素)。当这一天到来时，我们将使用这款相机进行闪烁体测试计划，因为它比EMCCD设备更具优势。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The goal of this works is to develop brighter, higher resolution scintilators that could improve the performance, and reduce the cost, of detectors designed for structural biology applications. The development is funded by a variety of SBIR grants from NIH and DOE but the testing of them under real beam conditions at 18ID is part of core project I in the BioCAT P41 grant. Currently we are examining films made of CsI:Tl,Sm, structured ZnTe:Om, and a structured ZnSe:Te as possible candidates for high brightness, high spatial resolution scintillators with fast decay times. The most promising of these so far is ZnSe:Te with 180% of the brightness of commercial MinR-2000 screens commonly used for these applications. These have been tested on 18ID with EMCCD and intensified CCD cameras to assess their suitability for the construction of time-resolved scattering detectors. Results of these experiments have been submitted for publication in NIM A. We will soon take delivery of an intensified CMOS camera capable of 3600 fps that we will ultimately be developed into a detector system (70 x 70 mm active area, ~67 micron pixels) when we have found a suitable scintillator. When this arrives we will be using this camera for the scintillator testing program because of it superiority over the EMCCD device.